Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA047115-10
Application #
6533123
Study Section
Pathology B Study Section (PTHB)
Program Officer
Sathyamoorthy, Neeraja
Project Start
1988-05-01
Project End
2005-07-31
Budget Start
2002-08-01
Budget End
2003-07-31
Support Year
10
Fiscal Year
2002
Total Cost
$260,379
Indirect Cost
Name
Wayne State University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Jin, Rongxian; Trikha, Mohit; Cai, Yinlong et al. (2007) A naturally occurring truncated beta3 integrin in tumor cells: native anti-integrin involved in tumor cell motility. Cancer Biol Ther 6:1559-68
Dome, Balazs; Raso, Erzsebet; Dobos, Judit et al. (2005) Parallel expression of alphaIIbbeta3 and alphavbeta3 integrins in human melanoma cells upregulates bFGF expression and promotes their angiogenic phenotype. Int J Cancer 116:27-35
Trikha, Mohit; Timar, Jozsef; Zacharek, Alex et al. (2002) Role for beta3 integrins in human melanoma growth and survival. Int J Cancer 101:156-67
Raso, E; Tovari, J; Toth, K et al. (2001) Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKC-mediated serine phosphorylation events in melanoma cells. Thromb Haemost 85:1037-42
Trikha, M; Raso, E; Cai, Y et al. (1998) Role of alphaII(b)beta3 integrin in prostate cancer metastasis. Prostate 35:185-92
Trikha, M; Cai, Y; Grignon, D et al. (1998) Identification of a novel truncated alphaIIb integrin. Cancer Res 58:4771-5
Timar, J; Trikha, M; Szekeres, K et al. (1998) Expression and function of the high affinity alphaIIbbeta3 integrin in murine melanoma cells. Clin Exp Metastasis 16:437-45
Trikha, M; Timar, J; Lundy, S K et al. (1997) The high affinity alphaIIb beta3 integrin is involved in invasion of human melanoma cells. Cancer Res 57:2522-8
Timar, J; Bazaz, R; Tang, D G et al. (1997) Post-translational regulation of surface integrin expression in tumor cells by 12(S)-HETE. Adv Exp Med Biol 400B:757-63
Tang, D G; Honn, K V (1997) Role of protein kinase C and phosphatases in 12(S)-HETE-induced tumor cell cytoskeletal reorganization. Adv Exp Med Biol 400A:349-61

Showing the most recent 10 out of 56 publications