Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA047668-08
Application #
2092687
Study Section
Pathology B Study Section (PTHB)
Project Start
1988-04-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cornell University
Department
Pathology
Type
Schools of Veterinary Medicine
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Beckley, Janel R; Pauli, Bendicht U; Elble, Randolph C (2004) Re-expression of detachment-inducible chloride channel mCLCA5 suppresses growth of metastatic breast cancer cells. J Biol Chem 279:41634-41
Cheng, Hung-Chi; Abdel-Ghany, Mossaad; Pauli, Bendicht U (2003) A novel consensus motif in fibronectin mediates dipeptidyl peptidase IV adhesion and metastasis. J Biol Chem 278:24600-7
Abdel-Ghany, Mossaad; Cheng, Hung-Chi; Elble, Randolph C et al. (2003) The interacting binding domains of the beta(4) integrin and calcium-activated chloride channels (CLCAs) in metastasis. J Biol Chem 278:49406-16
Elble, Randolph C; Ji, Guangju; Nehrke, Keith et al. (2002) Molecular and functional characterization of a murine calcium-activated chloride channel expressed in smooth muscle. J Biol Chem 277:18586-91
Abdel-Ghany, Mossaad; Cheng, Hung-Chi; Elble, Randolph C et al. (2002) Focal adhesion kinase activated by beta(4) integrin ligation to mCLCA1 mediates early metastatic growth. J Biol Chem 277:34391-400
Abdel-Ghany, M; Cheng, H C; Elble, R C et al. (2001) The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis. J Biol Chem 276:25438-46
Fuller, C M; Ji, H L; Tousson, A et al. (2001) Ca(2+)-activated Cl(-) channels: a newly emerging anion transport family. Pflugers Arch 443 Suppl 1:S107-10
Elble, R C; Pauli, B U (2001) Tumor suppression by a proapoptotic calcium-activated chloride channel in mammary epithelium. J Biol Chem 276:40510-7
Pauli, B U; Abdel-Ghany, M; Cheng, H C et al. (2000) Molecular characteristics and functional diversity of CLCA family members. Clin Exp Pharmacol Physiol 27:901-5
Gruber, A D; Pauli, B U (1999) Clustering of the human CLCA gene family on the short arm of chromosome 1 (1p22-31). Genome 42:1030-2

Showing the most recent 10 out of 38 publications