Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA049933-07
Application #
2093524
Study Section
Special Emphasis Panel (ZRG5-IMS (02))
Project Start
1989-07-24
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Hoyos, Beatrice; Jiang, Sulin; Hammerling, Ulrich (2005) Location and functional significance of retinol-binding sites on the serine/threonine kinase, c-Raf. J Biol Chem 280:6872-8
Korichneva, Irina; Hoyos, Beatrice; Chua, Ramon et al. (2002) Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen. J Biol Chem 277:44327-31
Hoyos, Beatrice; Imam, Asiya; Korichneva, Irina et al. (2002) Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids. J Biol Chem 277:23949-57
Hoyos, B; Imam, A; Chua, R et al. (2000) The cysteine-rich regions of the regulatory domains of Raf and protein kinase C as retinoid receptors. J Exp Med 192:835-45
Liu, C; Calogero, A; Ragona, G et al. (1996) EGR-1, the reluctant suppression factor: EGR-1 is known to function in the regulation of growth, differentiation, and also has significant tumor suppressor activity and a mechanism involving the induction of TGF-beta1 is postulated to account for this sup Crit Rev Oncog 7:101-25
Derguini, F; Nakanishi, K; Hammerling, U et al. (1994) Intracellular signaling activity of synthetic (14R)-, (14S)-, and (14RS)-14-hydroxy-4,14-retro-retinol. Biochemistry 33:623-8
Buck, J; Grun, F; Derguini, F et al. (1993) Anhydroretinol: a naturally occurring inhibitor of lymphocyte physiology. J Exp Med 178:675-80
Eppinger, T M; Buck, J; Hammerling, U (1993) Growth control or terminal differentiation: endogenous production and differential activities of vitamin A metabolites in HL-60 cells. J Exp Med 178:1995-2005
Garbe, A; Buck, J; Hammerling, U (1992) Retinoids are important cofactors in T cell activation. J Exp Med 176:109-17
Buck, J; Derguini, F; Levi, E et al. (1991) Intracellular signaling by 14-hydroxy-4,14-retro-retinol. Science 254:1654-6

Showing the most recent 10 out of 12 publications