Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050139-08
Application #
2093616
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1989-03-17
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Subbramanian, Ramu A; Charini, William A; Kuroda, Marcelo J et al. (2006) Expansion after epitope peptide exposure in vitro predicts cytotoxic T lymphocyte epitope dominance hierarchy in lymphocytes of vaccinated mamu-a*01+ rhesus monkeys. AIDS Res Hum Retroviruses 22:445-52
Greenland, John R; Liu, Huining; Berry, David et al. (2005) Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Mol Ther 12:164-70
Barouch, Dan H; Truitt, Diana M; Letvin, Norman L (2004) Expression kinetics of the interleukin-2/immunoglobulin (IL-2/Ig) plasmid cytokine adjuvant. Vaccine 22:3092-7
Seaman, Michael S; Peyerl, Fred W; Jackson, Shawn S et al. (2004) Subsets of memory cytotoxic T lymphocytes elicited by vaccination influence the efficiency of secondary expansion in vivo. J Virol 78:206-15
McKay, Paul F; Barouch, Dan H; Santra, Sampa et al. (2004) Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses. Eur J Immunol 34:1011-20
Zhang, Lei; Ribeiro, Ruy M; Mascola, John R et al. (2004) Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: implications for vaccination. J Virol 78:5520-2
McKay, Paul F; Barouch, Dan H; Schmitz, Jorn E et al. (2003) Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination. J Virol 77:4695-702
Barouch, Dan H; Kunstman, Jennifer; Glowczwskie, Jennifer et al. (2003) Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys. J Virol 77:7367-75
Barouch, Dan H; McKay, Paul F; Sumida, Shawn M et al. (2003) Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol 77:8729-35
Baig, Jamal; Levy, Daniel B; McKay, Paul F et al. (2002) Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination. J Virol 76:11484-90

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