Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA050616-06S2
Application #
2093889
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1990-12-07
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kansas
Department
Physiology
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Greenfeld, Chuck R; Roby, Katherine F; Pepling, Melissa E et al. (2007) Tumor necrosis factor (TNF) receptor type 2 is an important mediator of TNF alpha function in the mouse ovary. Biol Reprod 76:224-31
Arai, Koji Y; Roby, Katherine F; Terranova, Paul F (2005) Tumor necrosis factor alpha (TNF) suppresses cAMP response element (CRE) activity and nuclear CRE binding protein in MA-10 mouse Leydig tumor cells. Endocrine 27:17-24
Son, Deok-Soo; Arai, Koji Y; Roby, Katherine F et al. (2004) Tumor necrosis factor alpha (TNF) increases granulosa cell proliferation: dependence on c-Jun and TNF receptor type 1. Endocrinology 145:1218-26
Son, Deok-Soo; Roby, Katherine F; Terranova, Paul F (2004) Tumor necrosis factor-alpha induces serum amyloid A3 in mouse granulosa cells. Endocrinology 145:2245-52
Pengetnze, Yolande; Steed, Mary; Roby, Katherine F et al. (2003) Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line. Biochem Biophys Res Commun 309:377-83
Son, Deok-Soo; Roby, Katherine F; Rozman, Karl K et al. (2002) Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line. Toxicology 176:229-43
Rice, V M; Chaudhery, A R; Oluola, O et al. (2001) Herbimycin, a tyrosine kinase inhibitor with Src selectivity, reduces progesterone and estradiol secretion by human granulosa cells. Endocrine 15:271-6
Roby, K F; Taylor, C C; Sweetwood, J P et al. (2000) Development of a syngeneic mouse model for events related to ovarian cancer. Carcinogenesis 21:585-91
Montgomery Rice, V; Limback, S D; Roby, K F et al. (1999) Tumor necrosis factor alpha inhibition of follicle-stimulating hormone-induced granulosa cell estradiol secretion in the human does not involve reduction of cAMP secretion but inhibition at post-cAMP site(s). Endocrine 10:19-23
Roby, K F; Son, D S; Terranova, P F (1999) Alterations of events related to ovarian function in tumor necrosis factor receptor type I knockout mice. Biol Reprod 61:1616-21

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