Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058541-04
Application #
2099231
Study Section
Virology Study Section (VR)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Kong, Kathleen; Kumar, Manish; Taruishi, Midori et al. (2015) Adenovirus E4-ORF1 Dysregulates Epidermal Growth Factor and Insulin/Insulin-Like Growth Factor Receptors To Mediate Constitutive Myc Expression. J Virol 89:10774-85
Kumar, Manish; Kong, Kathleen; Javier, Ronald T (2014) Hijacking Dlg1 for oncogenic phosphatidylinositol 3-kinase activation in human epithelial cells is a conserved mechanism of human adenovirus E4-ORF1 proteins. J Virol 88:14268-77
Kong, Kathleen; Kumar, Manish; Taruishi, Midori et al. (2014) The human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinase. PLoS Pathog 10:e1004102
Ivanova, S; Gregorc, U; Vidergar, N et al. (2011) MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis. Cell Death Dis 2:e116
Javier, Ronald T; Rice, Andrew P (2011) Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses. J Virol 85:11544-56
Golebiewski, Lisa; Liu, Hongbing; Javier, Ronald T et al. (2011) The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions. J Virol 85:10639-48
Krishnapuram, R; Dhurandhar, E J; Dubuisson, O et al. (2011) Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab 300:E779-89
Irvin-Wilson, Charletha V; Newberg, Justin Y; Kong, Kathleen et al. (2011) High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells. Viruses 3:2396-411
Liu, Hongbing; Golebiewski, Lisa; Dow, Eugene C et al. (2010) The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. J Virol 84:11164-74
Chung, S-H; Weiss, R S; Frese, K K et al. (2008) Functionally distinct monomers and trimers produced by a viral oncoprotein. Oncogene 27:1412-20

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