Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058896-03
Application #
2099518
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037

  Publications

Grimster, Neil P; Connelly, Stephen; Baranczak, Aleksandra et al. (2013) Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate. J Am Chem Soc 135:5656-68
Bulawa, Christine E; Connelly, Stephen; Devit, Michael et al. (2012) Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc Natl Acad Sci U S A 109:9629-34
Witherden, Deborah A; Watanabe, Megumi; Garijo, Olivia et al. (2012) The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal ?? T cell function. Immunity 37:314-25
Kasmar, Anne G; van Rhijn, Ildiko; Cheng, Tan-Yun et al. (2011) CD1b tetramers bind ?? T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med 208:1741-7
Verdino, Petra; Witherden, Deborah A; Podshivalova, Katie et al. (2011) cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for ?? T cells. PLoS One 6:e19828
Kirchdoerfer, Robert N; Garner, Amanda L; Flack, Caralyn E et al. (2011) Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. J Biol Chem 286:17351-8
Verdino, Petra; Witherden, Deborah A; Ferguson, M Sharon et al. (2011) Molecular insights into ?? T cell costimulation by an anti-JAML antibody. Structure 19:80-9
Witherden, Deborah A; Verdino, Petra; Rieder, Stephanie E et al. (2010) The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science 329:1205-10
Verdino, Petra; Witherden, Deborah A; Havran, Wendy L et al. (2010) The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. Science 329:1210-4
Yoshida, Kenji; Corper, Adam L; Herro, Rana et al. (2010) The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity. J Clin Invest 120:1578-90

Showing the most recent 10 out of 88 publications