Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA059908-03
Application #
2100518
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1993-05-05
Project End
1997-02-28
Budget Start
1995-05-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Institute for Cancer Prevention
Department
Type
DUNS #
City
Valhalla
State
NY
Country
United States
Zip Code
10595
Lopez-Bergami, Pablo; Lau, Eric; Ronai, Ze'ev (2010) Emerging roles of ATF2 and the dynamic AP1 network in cancer. Nat Rev Cancer 10:65-76
Gaitonde, Supriya; De, Surya K; Tcherpakov, Marianna et al. (2009) BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma. Pigment Cell Melanoma Res 22:187-95
Bhoumik, Anindita; Lopez-Bergami, Pablo; Ronai, Ze'ev (2007) ATF2 on the double - activating transcription factor and DNA damage response protein. Pigment Cell Res 20:498-506
Elias, Bertha; Laine, Aaron; Ronai, Ze'ev (2005) Phosphorylation of MdmX by CDK2/Cdc2(p34) is required for nuclear export of Mdm2. Oncogene 24:2574-9
Broday, Limor; Kolotuev, Irina; Didier, Christine et al. (2004) The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans. Genes Dev 18:2380-91
Vargas, Dania Alarcon; Takahashi, Shoichi; Ronai, Ze'ev (2003) Mdm2: A regulator of cell growth and death. Adv Cancer Res 89:1-34
Buschmann, T; Lerner, D; Lee, C G et al. (2001) The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9. J Biol Chem 276:40389-95
Spiegelman, V S; Slaga, T J; Pagano, M et al. (2000) Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Mol Cell 5:877-82
Fuchs, S Y; Tappin, I; Ronai, Z (2000) Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation. J Biol Chem 275:12560-4
Fuchs, S Y; Ronai, Z (1999) Ubiquitination and degradation of ATF2 are dimerization dependent. Mol Cell Biol 19:3289-98

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