Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA061010-01S1
Application #
3204494
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1993-07-19
Project End
1997-06-30
Budget Start
1993-07-19
Budget End
1994-06-30
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Children's Research Institute
Department
Type
DUNS #
City
Washington
State
DC
Country
United States
Zip Code
20010
Dillinger, Barbara; Ahmadi-Erber, Sarah; Lau, Manuel et al. (2018) IFN-? and tumor gangliosides: Implications for the tumor microenvironment. Cell Immunol 325:33-40
Wondimu, Assefa; Liu, Yihui; Su, Yan et al. (2014) Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells. Cancer Res 74:5449-57
Liu, Yihui; Wondimu, Assefa; Yan, Su et al. (2014) Tumor gangliosides accelerate murine tumor angiogenesis. Angiogenesis 17:563-71
Lee, Hee Chul; Wondimu, Assefa; Liu, Yihui et al. (2012) Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. J Immunol 189:3521-7
Jales, Alessandra; Falahati, Rustom; Mari, Elisabeth et al. (2011) Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity. Immunology 132:134-43
Dong, Lixian; Liu, Yihui; Colberg-Poley, Anamaris M et al. (2011) Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function. Glycoconj J 28:137-47
Liu, Y; Yan, S; Wondimu, A et al. (2010) Ganglioside synthase knockout in oncogene-transformed fibroblasts depletes gangliosides and impairs tumor growth. Oncogene 29:3297-306
Shevchuk, Nikolai A; Hathout, Yetrib; Epifano, Olga et al. (2007) Alteration of ganglioside synthesis by GM3 synthase knockout in murine embryonic fibroblasts. Biochim Biophys Acta 1771:1226-34
Kaucic, Karen; Liu, Yihui; Ladisch, Stephan (2006) Modulation of growth factor signaling by gangliosides: positive or negative? Methods Enzymol 417:168-85
Shevchuk, Nikolai A; Bryksin, Anton V; Nusinovich, Yevgeniya A et al. (2004) Construction of long DNA molecules using long PCR-based fusion of several fragments simultaneously. Nucleic Acids Res 32:e19

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