Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA066561-01A1
Application #
2109965
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1996-04-01
Project End
2000-01-31
Budget Start
1996-04-01
Budget End
1997-01-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Delaware
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Thévenin, Anastasia F; Zony, Chati L; Bahnson, Brian J et al. (2011) Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts. Protein Expr Purif 75:138-46
Thévenin, Anastasia F; Zony, Chati L; Bahnson, Brian J et al. (2011) GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Sci 20:834-48
Huang, Yu-chu; Misquitta, Stephanie; Blond, Sylvie Y et al. (2008) Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits. J Biol Chem 283:32880-8
Ralat, Luis A; Misquitta, Stephanie A; Manevich, Yefim et al. (2008) Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Arch Biochem Biophys 474:109-18
Hearne, Jennifer L; Colman, Roberta F (2006) Catalytically active monomer of class mu glutathione transferase from rat. Biochemistry 45:5974-84
Ralat, Luis A; Manevich, Yefim; Fisher, Aron B et al. (2006) Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes. Biochemistry 45:360-72
Hearne, Jennifer L; Colman, Roberta F (2006) Contribution of the mu loop to the structure and function of rat glutathione transferase M1-1. Protein Sci 15:1277-89
Ralat, Luis A; Colman, Roberta F (2006) Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. Biochemistry 45:12491-9
Hearne, Jennifer L; Colman, Roberta F (2005) Delineation of xenobiotic substrate sites in rat glutathione S-transferase M1-1. Protein Sci 14:2526-36
Misquitta, Stephanie A; Colman, Roberta F (2005) Communication between the two active sites of glutathione S-transferase A1-1, probed using wild-type-mutant heterodimers. Biochemistry 44:8608-19

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