Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA066974-03S1
Application #
2716592
Study Section
Pathology B Study Section (PTHB)
Program Officer
Mohla, Suresh
Project Start
1996-04-15
Project End
2001-01-31
Budget Start
1998-02-01
Budget End
1999-01-31
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Sharma, Girdhar G; Hwang, Kyu-kye; Pandita, Raj K et al. (2003) Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol 23:8363-76
Hwang, Kyu-Kye; Worman, Howard J (2002) Gene regulation by human orthologs of Drosophila heterochromatin protein 1. Biochem Biophys Res Commun 293:1217-22
Hwang, K K; Eissenberg, J C; Worman, H J (2001) Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiers. Proc Natl Acad Sci U S A 98:11423-7
Ma, J; Hwang, K K; Worman, H J et al. (2001) Expression and functional analysis of three isoforms of human heterochromatin-associated protein HP1 in Drosophila. Chromosoma 109:536-44
Lin, F; Blake, D L; Callebaut, I et al. (2000) MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin. J Biol Chem 275:4840-7
Moss, S F; Krivosheyev, V; de Souza, A et al. (1999) Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms. Gut 45:723-9
Minc, E; Allory, Y; Worman, H J et al. (1999) Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. Chromosoma 108:220-34
Ostlund, C; Ellenberg, J; Hallberg, E et al. (1999) Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein. J Cell Sci 112 ( Pt 11):1709-19
Barton, R M; Worman, H J (1999) Prenylated prelamin A interacts with Narf, a novel nuclear protein. J Biol Chem 274:30008-18
Pierce, T; Worman, H J; Holy, J (1999) Neuronal differentiation of NT2/D1 teratocarcinoma cells is accompanied by a loss of lamin A/C expression and an increase in lamin B1 expression. Exp Neurol 157:241-50

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