Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA067946-10
Application #
6740821
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Perry, Mary Ellen
Project Start
1995-07-01
Project End
2006-08-31
Budget Start
2004-05-01
Budget End
2006-08-31
Support Year
10
Fiscal Year
2004
Total Cost
$262,500
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Internal Medicine/Medicine
Type
Other Domestic Higher Education
DUNS #
800772139
City
Houston
State
TX
Country
United States
Zip Code
77030
Izaguirre, Daisy I; Zhu, Wen; Hai, Tao et al. (2012) PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis. Mol Carcinog 51:895-906
Zhu, Wen; Hai, Tao; Ye, Lei et al. (2010) Medullary thyroid carcinoma cell lines contain a self-renewing CD133+ population that is dependent on ret proto-oncogene activity. J Clin Endocrinol Metab 95:439-44
Cheung, Hannah C; Hai, Tao; Zhu, Wen et al. (2009) Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain 132:2277-88
Hu, Jianhua; He, Xuming; Cote, Gilbert J et al. (2009) Singular Value Decomposition-based Alternative Splicing Detection. J Am Stat Assoc 104:944-953
Cheung, Hannah C; Baggerly, Keith A; Tsavachidis, Spiridon et al. (2008) Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays. BMC Genomics 9:216
Cheung, Hannah C; Corley, Lynda J; Fuller, Gregory N et al. (2006) Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol 19:1034-41
Bruno, Ivone G; Jin, Wei; Cote, Gilbert J (2004) Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet 13:2409-20
Jin, Wei; Cote, Gilbert J (2004) Enhancer-dependent splicing of FGFR1 alpha-exon is repressed by RNA interference-mediated down-regulation of SRp55. Cancer Res 64:8901-5
Jin, Wei; Bruno, Ivone G; Xie, Tong-Xin et al. (2003) Polypyrimidine tract-binding protein down-regulates fibroblast growth factor receptor 1 alpha-exon inclusion. Cancer Res 63:6154-7
Kikumori, Toyone; Cote, Gilbert J; Gagel, Robert F (2002) Naturally occurring heterologous trans-splicing of adenovirus RNA with host cellular transcripts during infection. FEBS Lett 522:41-6

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