Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA069408-01
Application #
2113486
Study Section
Genetics Study Section (GEN)
Project Start
1996-03-05
Project End
2000-12-31
Budget Start
1996-03-05
Budget End
1996-12-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Genetics
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Chabu, Chiswili; Li, Da-Ming; Xu, Tian (2017) EGFR/ARF6 regulation of Hh signalling stimulates oncogenic Ras tumour overgrowth. Nat Commun 8:14688
Ma, Xianjue; Lu, Jin-Yu; Dong, Yongli et al. (2017) PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-Dependent Tumor Growth and Invasion. Cell Rep 19:2657-2664
Willsey, Helen Rankin; Zheng, Xiaoyan; Carlos Pastor-Pareja, José et al. (2016) Localized JNK signaling regulates organ size during development. Elife 5:
Gayle, Sophia; Pan, Yukun; Landrette, Sean et al. (2015) piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation. Stem Cell Reports 4:926-38
Mishra-Gorur, Ketu; Ça?layan, Ahmet Okay; Schaffer, Ashleigh E et al. (2014) Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors. Neuron 84:1226-39
Chabu, Chiswili; Xu, Tian (2014) Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth. Development 141:4729-39
Ma, X; Li, W; Yu, H et al. (2014) Bendless modulates JNK-mediated cell death and migration in Drosophila. Cell Death Differ 21:407-15
Du, Xingrong; Dong, Yongli; Shi, Hao et al. (2014) Mst1 and mst2 are essential regulators of trophoblast differentiation and placenta morphogenesis. PLoS One 9:e90701
Pastor-Pareja, José Carlos; Xu, Tian (2013) Dissecting social cell biology and tumors using Drosophila genetics. Annu Rev Genet 47:51-74
Pastor-Pareja, José Carlos; Xu, Tian (2011) Shaping cells and organs in Drosophila by opposing roles of fat body-secreted Collagen IV and perlecan. Dev Cell 21:245-56

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