Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA069480-01
Application #
2113542
Study Section
Pathology B Study Section (PTHB)
Project Start
1996-06-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Henry Ford Health System
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073134603
City
Detroit
State
MI
Country
United States
Zip Code
48202

  Publications

Ilmer, Matthias; Mazurek, Nachman; Gilcrease, Michael Z et al. (2016) Low expression of galectin-3 is associated with poor survival in node-positive breast cancers and mesenchymal phenotype in breast cancer stem cells. Breast Cancer Res 18:97
Mazurek, N; Byrd, J C; Sun, Y et al. (2012) Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells. Cell Death Differ 19:523-33
Song, Shumei; Ji, Baoan; Ramachandran, Vijaya et al. (2012) Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling. PLoS One 7:e42699
Song, Shumei; Byrd, James C; Guha, Sushovan et al. (2011) Induction of MUC5AC mucin by conjugated bile acids in the esophagus involves the phosphatidylinositol 3-kinase/protein kinase C/activator protein-1 pathway. Cancer 117:2386-97
Mazurek, Nachman; Byrd, James C; Sun, Yunjie et al. (2011) A galectin-3 sequence polymorphism confers TRAIL sensitivity to human breast cancer cells. Cancer 117:4375-80
Song, Shumei; Krishnan, Koyamangalath; Liu, Kaifeng et al. (2009) Polyphenon E inhibits the growth of human Barrett's and aerodigestive adenocarcinoma cells by suppressing cyclin D1 expression. Clin Cancer Res 15:622-31
Song, Shumei; Mazurek, Nachman; Liu, Chunming et al. (2009) Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res 69:1343-9
Song, Shumei; Guha, Sushovan; Liu, Kaifeng et al. (2007) COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma. Gut 56:1512-21
Mazurek, Nachman; Sun, Yun Jie; Liu, Kai-Feng et al. (2007) Phosphorylated galectin-3 mediates tumor necrosis factor-related apoptosis-inducing ligand signaling by regulating phosphatase and tensin homologue deleted on chromosome 10 in human breast carcinoma cells. J Biol Chem 282:21337-48
Holt, Peter R; Bresalier, Robert S; Ma, Chan K et al. (2006) Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa. Cancer 106:287-96

Showing the most recent 10 out of 31 publications