Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA070810-01
Application #
2114611
Study Section
Virology Study Section (VR)
Project Start
1996-06-25
Project End
2000-03-31
Budget Start
1996-06-25
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Wickersham, Ian R; Lyon, David C; Barnard, Richard J O et al. (2007) Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron 53:639-47
Babel, Angeline Rose; Bruce, James; Young, John A T (2007) The hr1 and fusion peptide regions of the subgroup B avian sarcoma and leukosis virus envelope glycoprotein influence low pH-dependent membrane fusion. PLoS One 2:e171
Bruce, James W; Bradley, Kenneth A; Ahlquist, Paul et al. (2005) Isolation of cell lines that show novel, murine leukemia virus-specific blocks to early steps of retroviral replication. J Virol 79:12969-78
Lim, Kwang-Il; Narayan, Shakti; Young, John A T et al. (2004) Effects of lipid rafts on dynamics of retroviral entry and trafficking: Quantitative analysis. Biotechnol Bioeng 86:650-60
Melikyan, G B; Barnard, R J O; Markosyan, R M et al. (2004) Low pH is required for avian sarcoma and leukosis virus Env-induced hemifusion and fusion pore formation but not for pore growth. J Virol 78:3753-62
Narayan, Shakti; Young, John A T (2004) Reconstitution of retroviral fusion and uncoating in a cell-free system. Proc Natl Acad Sci U S A 101:7721-6
Barnard, Richard J O; Narayan, Shakti; Dornadula, Geethanjali et al. (2004) Low pH is required for avian sarcoma and leukosis virus Env-dependent viral penetration into the cytosol and not for viral uncoating. J Virol 78:10433-41
Narayan, Shakti; Barnard, Richard J O; Young, John A T (2003) Two retroviral entry pathways distinguished by lipid raft association of the viral receptor and differences in viral infectivity. J Virol 77:1977-83
Yu, Xuemei; Wang, Qing-Yin; Guo, Ying et al. (2003) Kinetic analysis of binding interaction between the subgroup A Rous sarcoma virus glycoprotein SU and its cognate receptor Tva: calcium is not required for ligand binding. J Virol 77:7517-26
Barnard, R J O; Young, J A T (2003) Alpharetrovirus envelope-receptor interactions. Curr Top Microbiol Immunol 281:107-36

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