Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA070823-04
Application #
6128307
Study Section
Radiation Study Section (RAD)
Program Officer
Stone, Helen B
Project Start
1996-12-15
Project End
2004-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
4
Fiscal Year
2000
Total Cost
$235,463
Indirect Cost
Name
Medical College of Wisconsin
Department
Biochemistry
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Fahey, Jonathan M; Stancill, Jennifer S; Smith, Brian C et al. (2018) Nitric oxide antagonism to glioblastoma photodynamic therapy and mitigation thereof by BET bromodomain inhibitor JQ1. J Biol Chem 293:5345-5359
Girotti, Albert W; Korytowski, Witold (2018) Cholesterol Peroxidation as a Special Type of Lipid Oxidation in Photodynamic Systems. Photochem Photobiol :
Fahey, Jonathan M; Girotti, Albert W (2017) Nitric oxide-mediated resistance to photodynamic therapy in a human breast tumor xenograft model: Improved outcome with NOS2 inhibitors. Nitric Oxide 62:52-61
Bazak, Jerzy; Fahey, Jonathan M; Wawak, Katarzyna et al. (2017) Bystander effects of nitric oxide in anti-tumor photodynamic therapy. Cancer Cell Microenviron 4:
Girotti, Albert W; Korytowski, Witold (2017) Cholesterol Hydroperoxide Generation, Translocation, and Reductive Turnover in Biological Systems. Cell Biochem Biophys 75:413-419
Girotti, Albert W; Korytowski, Witold (2016) Cholesterol as a natural probe for free radical-mediated lipid peroxidation in biological membranes and lipoproteins. J Chromatogr B Analyt Technol Biomed Life Sci 1019:202-9
Girotti, Albert W (2016) Modulation of the Anti-Tumor Efficacy of Photodynamic Therapy by Nitric Oxide. Cancers (Basel) 8:
Fahey, Jonathan M; Emmer, Joseph V; Korytowski, Witold et al. (2016) Antagonistic Effects of Endogenous Nitric Oxide in a Glioblastoma Photodynamic Therapy Model. Photochem Photobiol 92:842-853
Girotti, Albert W (2015) Tumor-generated nitric oxide as an antagonist of photodynamic therapy. Photochem Photobiol Sci 14:1425-32
Fahey, Jonathan M; Girotti, Albert W (2015) Accelerated migration and invasion of prostate cancer cells after a photodynamic therapy-like challenge: Role of nitric oxide. Nitric Oxide 49:47-55

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