Goldstein, Michael; Kastan, Michael B (2015) Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding. Cancer Res 75:2699-707
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Goldstein, Michael; Derheimer, Frederick A; Tait-Mulder, Jacqueline et al. (2013) Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair. Proc Natl Acad Sci U S A 110:16874-9
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Lim, Yiting; Hedayati, Mohammad; Merchant, Akil A et al. (2012) Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation. Int J Radiat Oncol Biol Phys 84:800-6
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Valentin-Vega, Yasmine A; Maclean, Kirsteen H; Tait-Mulder, Jacqueline et al. (2012) Mitochondrial dysfunction in ataxia-telangiectasia. Blood 119:1490-500
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Derheimer, Frederick A; Kastan, Michael B (2010) Multiple roles of ATM in monitoring and maintaining DNA integrity. FEBS Lett 584:3675-81
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Alexander, Angela; Cai, Sheng-Li; Kim, Jinhee et al. (2010) ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci U S A 107:4153-8
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Tang, Xi; Hui, Zhou-Guang; Cui, Xiao-Li et al. (2008) A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage. Mol Cell Biol 28:2559-66
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Maclean, Kirsteen H; Dorsey, Frank C; Cleveland, John L et al. (2008) Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. J Clin Invest 118:79-88
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Berkovich, Elijahu; Monnat Jr, Raymond J; Kastan, Michael B (2008) Assessment of protein dynamics and DNA repair following generation of DNA double-strand breaks at defined genomic sites. Nat Protoc 3:915-22
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Kastan, Michael B (2008) DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture. Mol Cancer Res 6:517-24
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