About 1 in 90 American children born in the late 1990's will develop malignant melanoma in their lifetimes. Sun exposure in childhood appears to be the most important preventable risk factor for this disease. This study will continue to follow a previously enrolled cohort (n=728) that participated in a randomized trial of a provider-delivered sun protection intervention while children were between the ages of 0 and 3 years. The study will also enroll an additional 900 children who are part of the same birth cohort from 1998. Subjects in both the original cohort and new cohort will be randomly assigned to intervention and control groups; the intervention group will receive a series of tailored newsletters aimed at increasing sun protection over a 3-year intervention period. This tailored intervention is based on the Precaution Adoption Process Model, which focuses on increasing personal perceptions of risk. The effectiveness of the intervention in increasing sun protection of children will be evaluated through telephone surveys of parents at four time-points (upon enrollment and 1, 2, and 3 years later), and through skin exams of all children at the same time-points. Skin exams will provide objective measures of sun exposure using spectrophotometry, assessment of freckling, and enumeration of moles (nevi). This evaluation will assess the long-term effectiveness of the previous provider delivered intervention, the effectiveness of the tailored intervention as a """"""""booster"""""""" to the provider intervention, and the effectiveness of the tailored intervention alone. The study also includes a longitudinal study of mole development, which will assess the relationships between sun exposure, """"""""host traits"""""""" (such as skin, hair, and eye color, tendency to burn vs. tan, tendency to freckle), and development of nevi, the strongest predictor for malignant melanoma. The study also includes a cost analysis, which will focus on the costs associated with intervention delivery, behavior change, and mole avoidance. If this intervention proves to be effective in increasing sun protection of children, cost and efficiency will be key factors in dissemination and adoption of the intervention. ? ?
| Asdigian, Nancy L; Barón, Anna E; Morelli, Joseph G et al. (2018) Trajectories of Nevus Development From Age 3 to 16 Years in the Colorado Kids Sun Care Program Cohort. JAMA Dermatol 154:1272-1280 |
| Joselow, Andrew; Lynn, Darren; Terzian, Tamara et al. (2017) Senescence-Like Phenotypes in Human Nevi. Methods Mol Biol 1534:175-184 |
| Barón, Anna E; Asdigian, Nancy L; Gonzalez, Victoria et al. (2014) Interactions between ultraviolet light and MC1R and OCA2 variants are determinants of childhood nevus and freckle phenotypes. Cancer Epidemiol Biomarkers Prev 23:2829-39 |
| Tran, Alexander D; Aalborg, Jenny; Asdigian, Nancy L et al. (2012) Parents' perceptions of skin cancer threat and children's physical activity. Prev Chronic Dis 9:E143 |
| Crane, Lori A; Asdigian, Nancy L; Barón, Anna E et al. (2012) Mailed intervention to promote sun protection of children: a randomized controlled trial. Am J Prev Med 43:399-410 |
| Gamble, Ryan G; Asdigian, Nancy L; Aalborg, Jenny et al. (2012) Sun damage in ultraviolet photographs correlates with phenotypic melanoma risk factors in 12-year-old children. J Am Acad Dermatol 67:587-97 |
| Aalborg, Jenny; Morelli, Joseph G; Byers, Tim E et al. (2010) Effect of hair color and sun sensitivity on nevus counts in white children in Colorado. J Am Acad Dermatol 63:430-9 |
| Crane, Lori A; Mokrohisky, Stefan T; Dellavalle, Robert P et al. (2009) Melanocytic nevus development in Colorado children born in 1998: a longitudinal study. Arch Dermatol 145:148-56 |
| Juhl, Ashley L; Byers, Tim E; Robinson, William A et al. (2009) The anatomic distribution of melanoma and relationships with childhood nevus distribution in Colorado. Melanoma Res 19:252-9 |
| Aalborg, Jenny; Morelli, Joseph G; Mokrohisky, Stefan T et al. (2009) Tanning and increased nevus development in very-light-skinned children without red hair. Arch Dermatol 145:989-96 |
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