Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA000576-12
Application #
3939844
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Type
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Mayer, D J; Kellstein, D E (1992) Cholecystokinin and opiate interactions. Clin Neuropharmacol 15 Suppl 1 Pt A:477A-478A
Mao, J; Coghill, R C; Kellstein, D E et al. (1992) Calcitonin gene-related peptide enhances substance P-induced behaviors via metabolic inhibition: in vivo evidence for a new mechanism of neuromodulation. Brain Res 574:157-63
Leshem, M; Frenk, H; Coghill, R C et al. (1991) Paradoxical opiate specific paralytic effects of high doses of intracerebroventricular etorphine and fentanyl in rats. Pharmacol Biochem Behav 38:475-8
Kellstein, D E; Mayer, D J (1991) Spinal co-administration of cholecystokinin antagonists with morphine prevents the development of opioid tolerance. Pain 47:221-9
Kellstein, D E; Price, D D; Mayer, D J (1991) Cholecystokinin and its antagonist lorglumide respectively attenuate and facilitate morphine-induced inhibition of C-fiber evoked discharges of dorsal horn nociceptive neurons. Brain Res 540:302-6
Bossut, D F; Huang, Z S; Sun, S L et al. (1991) Electroacupuncture in rats: evidence for naloxone and naltrexone potentiation of analgesia. Brain Res 549:36-46
Bossut, D F; Mayer, D J (1991) Electroacupuncture analgesia in rats: naltrexone antagonism is dependent on previous exposure. Brain Res 549:47-51
Bossut, D F; Mayer, D J (1991) Electroacupuncture analgesia in naive rats: effects of brainstem and spinal cord lesions, and role of pituitary-adrenal axis. Brain Res 549:52-8
Frenk, H; Miller, J; Johannessen, J N et al. (1990) Spinal paralysis and catalepsy induced by intrathecal injection of opioid agonists. Pharmacol Biochem Behav 36:243-7
Kellstein, D E; Mayer, D J (1990) Chronic administration of cholecystokinin antagonists reverses the enhancement of spinal morphine analgesia induced by acute pretreatment. Brain Res 516:263-70

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