The overall goals of this longitudinal study are to examine the etiologic determinants of young adult drug use/abuse and the consequences of use on the individual's functioning. The original sample in 1975 consisted of 976 mothers whose children's average age was 5 (T1). Subsequently, children and their mothers were interviewed when the children's average age was 13 (T2), 15 (T3), and 21 (T4). At T5, only the youth (average age 26) was interviewed. A sixth data collection (T6) is proposed to accomplish the following: (1) to examine interrelations and interactions of personality, family, peer, and ecological factors (starting in early childhood) as they affect the course of drug use/abuse over time (i.e., onset, stability, and change); and (2) to study the consequences of long-term drug use of adult intra- and interpersonal functioning. As in the past, separate interviews with young adults will be conducted in their own homes by trained interviewers. Scales with adequate psychometric properties measuring the independence variables will be developed from the interview schedules. The primary analytic techniques will be causal analysis and/or hierarchial or logistic regression. The significance of this study lies in its longitudinal design with in-depth intra- and interpersonal data available at several crucial stages of development. These data allow us not only to examine the pathways to drug use/abuse from the very beginning but also to study the course of drug behavior over time, i.e., the factors related to the subject's becoming more (or less) involved in drug use/abuse over a span of years. Such knowledge will help pinpoint those adolescents/young adults at risk for increased drug involvement and will provide detailed and specific guidelines for prevention and treatment. Our longitudinal study of the consequences of drug use is unique in that the long-term effects of use can be evaluated to see if their impact is cumulative. Identification of childhood and adolescent factors that can mitigate or compensate for the impact of drug consequences on later functioning would provide additional aids for effective prevention and treatment efforts.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
7R01DA003188-23
Application #
6845516
Study Section
Special Emphasis Panel (ZDA1-KXN-G (29))
Program Officer
Chambers, Jessica Campbell
Project Start
1995-03-15
Project End
2005-02-28
Budget Start
2004-01-01
Budget End
2004-02-29
Support Year
23
Fiscal Year
2003
Total Cost
$378,663
Indirect Cost
Name
New York University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Zhang, Chenshu; Brook, Judith S; Leukefeld, Carl G et al. (2017) Lack of Preventive Health Behaviors in the Early Forties: The Role of Earlier Trajectories of Cigarette Smoking From Adolescence to Adulthood. Subst Use Misuse 52:1527-1537
Brook, Judith S; Balka, Elinor B; Zhang, Chenshu et al. (2017) ADHD, Conduct Disorder, Substance Use Disorder, and Nonprescription Stimulant Use. J Atten Disord 21:776-782
Zhang, Chenshu; Brook, Judith S; Leukefeld, Carl G et al. (2016) Longitudinal psychosocial factors related to symptoms of Internet addiction among adults in early midlife. Addict Behav 62:65-72
Brook, Judith S; Zhang, Chenshu; Leukefeld, Carl G et al. (2016) Marijuana use from adolescence to adulthood: developmental trajectories and their outcomes. Soc Psychiatry Psychiatr Epidemiol 51:1405-1415
Zhang, Chenshu; Brook, Judith S; Leukefeld, Carl G et al. (2016) Trajectories of marijuana use from adolescence to adulthood as predictors of unemployment status in the early forties. Am J Addict 25:203-9
Pahl, Kerstin; Brook, Judith S; Zhang, Chenshu et al. (2016) Psychosocial Predictors of Mental Health Service Utilization Among Women During their Mid-Sixties. J Behav Health Serv Res 43:143-54
Zhang, Chenshu; Brook, Judith S; Leukefeld, Carl G et al. (2016) Psychosocial Factors Related to Underuse of Medical Services. J Urban Health 93:652-65
Zhang, Chenshu; Brook, Judith S; Leukefeld, Carl G et al. (2016) Associations between compulsive buying and substance dependence/abuse, major depressive episodes, and generalized anxiety disorder among men and women. J Addict Dis 35:298-304
Brook, Judith S; Zhang, Chenshu; Brook, David W et al. (2015) Compulsive buying: Earlier illicit drug use, impulse buying, depression, and adult ADHD symptoms. Psychiatry Res 228:312-7
Brook, Judith S; Balka, Elinor B; Zhang, Chenshu et al. (2015) Longitudinal Smoking Patterns: Do They Predict Symptoms of ADHD in Adults? J Atten Disord :

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