To better understand the role of treatment over time and the factors that extend its benefits are major concerns of the substance abuse field. This is a competing continuation of a longitudinal study of 1204 managed care (Kaiser Permanente) substance abuse treatment patients who were first interviewed in 1994 in a randomized controlled comparison of day hospital and traditional outpatient programs. We propose to collect 9- and 11-year data and use growth curve models and other analytic tools to examine factors influencing 11-year trajectories of substance use, readmission, medical outcomes, utilization, and cost. Survey data (with drug testing) have been collected at baseline, during treatment, 6 and 12 months, and 5 and 7 years. The health plan documents all substance abuse treatment visits and services, and all medical and psychiatric diagnoses, services received, and costs. We also include a sample of Kaiser members matched with our sample on age, gender, and length of enrollment. These data sources combined afford an opportunity to examine the medical, psychiatric, and substance abuse outcomes, utilization and costs of a well-characterized sample of commercially insured substance abuse treatment patients. To date, there have been no long-term studies in HMO's, although they are a major treatment provider in both the private and public sectors. We build on critical findings from our study to date: we found important differences in the course of problems by gender, age, psychiatric comorbidity, and type of dependence that suggest the need for greater attention to questions about use of medical and psychiatric services, and NA/AA and social networks. We also found patterns in health disparities, particularly how loss of insurance influences the course of problems overtime. Drawing from models of health services utilization and treatment careers, we study explanatory factors: individual/characteristics (demographic, substance use, psychiatric, and medical conditions, and other social functioning), treatment characteristics (number and patterns of substance abuse treatment episodes and services received), and extra-treatment characteristics (medical and psychiatric services, recovery-oriented social networks, and self-help affiliation). We use this model to address questions such as: Do multiple treatment episodes build on one another? Does regular primary care reinforce treatment benefits over time? Will the younger group show the same maturation effects over 11 years seen in community samples? How does the course of substance use affect medical conditions? What are the predictors of mortality? How valid are self reports of substance use and medical utilization? The study tests """"""""real world"""""""" use of substance abuse, medical, and psychiatric services and has important implications for developing a continuing care approach to treatment.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA008728-14
Application #
7275936
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Duffy, Sarah Q
Project Start
1993-09-30
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
14
Fiscal Year
2007
Total Cost
$438,472
Indirect Cost
Name
University of California San Francisco
Department
Psychiatry
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Chi, Felicia W; Weisner, Constance; Grella, Christine E et al. (2014) Does age at first treatment episode make a difference in outcomes over 11 years? J Subst Abuse Treat 46:482-90
Witbrodt, Jane; Ye, Yu; Bond, Jason et al. (2014) Alcohol and drug treatment involvement, 12-step attendance and abstinence: 9-year cross-lagged analysis of adults in an integrated health plan. J Subst Abuse Treat 46:412-9
Parthasarathy, Sujaya; Chi, Felicia W; Mertens, Jennifer R et al. (2012) The role of continuing care in 9-year cost trajectories of patients with intakes into an outpatient alcohol and drug treatment program. Med Care 50:540-6
Sterling, Stacy; Chi, Felicia; Hinman, Agatha (2011) Integrating care for people with co-occurring alcohol and other drug, medical, and mental health conditions. Alcohol Res Health 33:338-49
Chi, Felicia W; Parthasarathy, Sujaya; Mertens, Jennifer R et al. (2011) Continuing care and long-term substance use outcomes in managed care: early evidence for a primary care-based model. Psychiatr Serv 62:1194-200
Chou, Chih-Ping; Chi, Felicia; Weisner, Constance et al. (2010) Initial Status in Growth Curve Modeling for Randomized Trials. J Drug Issues 40:155-172
Weisner, Constance; Hinman, Agatha; Lu, Yun et al. (2010) Addiction treatment ultimatums and U.S. health reform: A case study. Nordisk Alkohol Nark 27:685-698
Chi, Felicia W; Weisner, Constance M (2008) Nine-year psychiatric trajectories and substance use outcomes: an application of the group-based modeling approach. Eval Rev 32:39-58
Satre, Derek D; Blow, Frederic C; Chi, Felicia W et al. (2007) Gender differences in seven-year alcohol and drug treatment outcomes among older adults. Am J Addict 16:216-21
Mertens, Jennifer R; Weisner, Constance M; Ray, G Thomas (2005) Readmission among chemical dependency patients in private, outpatient treatment: patterns, correlates and role in long-term outcome. J Stud Alcohol 66:842-7

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