|
Lazenka, Matthew L; Moerke, Megan J; Townsend, E Andrew et al. (2018) Dissociable effects of the kappa opioid receptor agonist nalfurafine on pain/itch-stimulated and pain/itch-depressed behaviors in male rats. Psychopharmacology (Berl) 235:203-213
|
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Kormos, Chad M; Ondachi, Pauline W; Runyon, Scott P et al. (2017) Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists. ACS Med Chem Lett 8:742-745
|
|
Wells, Audrey M; Ridener, Elysia; Bourbonais, Clinton A et al. (2017) Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism. J Neurosci 37:7656-7668
|
|
Runyon, Scott P; Kormos, Chad M; Gichinga, Moses G et al. (2016) Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor Antagonists. J Org Chem 81:10383-10391
|
|
Kormos, Chad M; Gichinga, Moses G; Runyon, Scott P et al. (2016) Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres. Bioorg Med Chem 24:3842-8
|
|
Donahue, Rachel J; Landino, Samantha M; Golden, Sam A et al. (2015) Effects of acute and chronic social defeat stress are differentially mediated by the dynorphin/kappa-opioid receptor system. Behav Pharmacol 26:654-63
|
|
Buda, Jeffrey J; Carroll, F I; Kosten, Thomas R et al. (2015) A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic. Neuropsychopharmacology 40:2059-65
|
|
Taylor, A M W; Roberts, K W; Pradhan, A A et al. (2015) Anti-nociception mediated by a ? opioid receptor agonist is blocked by a ? receptor agonist. Br J Pharmacol 172:691-703
|
|
Carroll, F Ivy; Gichinga, Moses G; Kormos, Chad M et al. (2015) Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituents. Bioorg Med Chem 23:6379-88
|
|
Kormos, Chad M; Cueva, Juan Pablo; Gichinga, Moses G et al. (2014) Effect of the 3- and 4-methyl groups on the opioid receptor properties of N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines. J Med Chem 57:3140-7
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