This is a proposal for a broad-based study of binaural hearing. The goal is to develop an integrated understanding of the processing of sound by the two ears, and to apply this understanding to improving the functional hearing abilities of people with hearing impairments or neurological disorders. This program contains extensive interplay between psychophysical studies and theoretical modeling. The proposed work incorporates theoretical studies of both physiological and psychophysical phenomena for both normal and abnormal auditory systems. -Proposed experimental studies include psychophysical studies of listeners with normal hearing as well as psychophysical studies of subjects with hearing losses or neurological disorders. Since it is a primary goal to investigate the relation of psychophysical performance to physiological mechanisms, considerable work is proposed to develop quantitative models of the processing of neural patterns by brainstem neurons that are sensitive to binaural stimulation and to incorporate descriptions of the physiological activity of these neurons into models of the psychophysical abilities of normal and impaired listeners. Measurements on impaired listeners include headphone and free-field measurements and will test classical psychophysical abilities as well as the processing of complex sound fields. Binaural hearing tests will be developed to isolate the specific difficulties of impaired listeners, and signal processing schemes will be recommended to minimize. the impact of these difficulties for listening in complex (noisy and reverberant) environments.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000100-21
Application #
2124569
Study Section
Hearing Research Study Section (HAR)
Project Start
1988-04-01
Project End
1998-03-31
Budget Start
1995-04-01
Budget End
1996-03-31
Support Year
21
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Boston University
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Best, Virginia; Mason, Christine R; Swaminathan, Jayaganesh et al. (2017) Use of a glimpsing model to understand the performance of listeners with and without hearing loss in spatialized speech mixtures. J Acoust Soc Am 141:81
Mi, Jing; Groll, Matti; Colburn, H Steven (2017) Comparison of a target-equalization-cancellation approach and a localization approach to source separation. J Acoust Soc Am 142:2933
Spencer, Nathaniel J; Hawley, Monica L; Colburn, H Steven (2016) Relating interaural difference sensitivities for several parameters measured in normal-hearing and hearing-impaired listeners. J Acoust Soc Am 140:1783
Mi, Jing; Colburn, H Steven (2016) A Binaural Grouping Model for Predicting Speech Intelligibility in Multitalker Environments. Trends Hear 20:
Dong, Junzi; Colburn, H Steven; Sen, Kamal (2016) Cortical Transformation of Spatial Processing for Solving the Cocktail Party Problem: A Computational Model(1,2,3). eNeuro 3:
Swaminathan, Jayaganesh; Mason, Christine R; Streeter, Timothy M et al. (2016) Role of Binaural Temporal Fine Structure and Envelope Cues in Cocktail-Party Listening. J Neurosci 36:8250-7
Chung, Yoojin; Delgutte, Bertrand; Colburn, H Steven (2015) Modeling binaural responses in the auditory brainstem to electric stimulation of the auditory nerve. J Assoc Res Otolaryngol 16:135-58
Wang, Le; Devore, Sasha; Delgutte, Bertrand et al. (2014) Dual sensitivity of inferior colliculus neurons to ITD in the envelopes of high-frequency sounds: experimental and modeling study. J Neurophysiol 111:164-81
Wan, Rui; Durlach, Nathaniel I; Colburn, H Steven (2014) Application of a short-time version of the Equalization-Cancellation model to speech intelligibility experiments with speech maskers. J Acoust Soc Am 136:768-76
Kidd Jr, Gerald; Mason, Christine R; Streeter, Timothy et al. (2013) Perceiving sequential dependencies in auditory streams. J Acoust Soc Am 134:1215-31

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