Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000139-16
Application #
2124797
Study Section
Hearing Research Study Section (HAR)
Project Start
1979-07-01
Project End
1996-12-31
Budget Start
1995-04-01
Budget End
1996-12-31
Support Year
16
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Surgery
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Lim, Hyun Woo; Pak, Kwang; Ryan, Allen F et al. (2018) Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage. Front Cell Neurosci 12:179
Noack, Volker; Pak, Kwang; Jalota, Rahul et al. (2017) An Antioxidant Screen Identifies Candidates for Protection of Cochlear Hair Cells from Gentamicin Toxicity. Front Cell Neurosci 11:242
Masuda, Masatsugu; Li, Yan; Pak, Kwang et al. (2017) The Promoter and Multiple Enhancers of the pou4f3 Gene Regulate Expression in Inner Ear Hair Cells. Mol Neurobiol 54:5414-5426
Ryan, Allen F; Kujawa, Sharon G; Hammill, Tanisha et al. (2016) Temporary and Permanent Noise-induced Threshold Shifts: A Review of Basic and Clinical Observations. Otol Neurotol 37:e271-5
Taura, A; Taura, K; Koyama, Y et al. (2016) Hair cell stereociliary bundle regeneration by espin gene transduction after aminoglycoside damage and hair cell induction by Notch inhibition. Gene Ther 23:415-23
Ryan, Allen F; Ikeda, Ryoukichi; Masuda, Masatsugu (2015) The regulation of gene expression in hair cells. Hear Res 329:33-40
Froud, Kristina E; Wong, Ann Chi Yan; Cederholm, Jennie M E et al. (2015) Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. Nat Commun 6:7115
Morton-Jones, Rachel T; Vlajkovic, Srdjan M; Thorne, Peter R et al. (2015) Properties of ATP-gated ion channels assembled from P2X2 subunits in mouse cochlear Reissner's membrane epithelial cells. Purinergic Signal 11:551-60
Ikeda, Ryoukichi; Pak, Kwang; Chavez, Eduardo et al. (2015) Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells. Mol Neurobiol 51:672-84
Wong, Ann C Y; Ryan, Allen F (2015) Mechanisms of sensorineural cell damage, death and survival in the cochlea. Front Aging Neurosci 7:58

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