Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
1R01DC003055-01
Application #
2128554
Study Section
Sensory Disorders and Language Study Section (CMS)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Physiology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Howitt, Michael R; Lavoie, Sydney; Michaud, Monia et al. (2016) Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science 351:1329-33
Lewandowski, Brian C; Sukumaran, Sunil K; Margolskee, Robert F et al. (2016) Amiloride-Insensitive Salt Taste Is Mediated by Two Populations of Type III Taste Cells with Distinct Transduction Mechanisms. J Neurosci 36:1942-53
Sukumaran, Sunil K; Yee, Karen K; Iwata, Shusuke et al. (2016) Taste cell-expressed ?-glucosidase enzymes contribute to gustatory responses to disaccharides. Proc Natl Acad Sci U S A 113:6035-40
Takai, Shingo; Yasumatsu, Keiko; Inoue, Mayuko et al. (2015) Glucagon-like peptide-1 is specifically involved in sweet taste transmission. FASEB J 29:2268-80
Lee, Robert J; Kofonow, Jennifer M; Rosen, Philip L et al. (2014) Bitter and sweet taste receptors regulate human upper respiratory innate immunity. J Clin Invest 124:1393-405
Kokrashvili, Zaza; Yee, Karen K; Ilegems, Erwin et al. (2014) Endocrine taste cells. Br J Nutr 111 Suppl 1:S23-9
Mokadem, Mohamad; Zechner, Juliet F; Margolskee, Robert F et al. (2014) Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency. Mol Metab 3:191-201
Ren, Wenwen; Lewandowski, Brian C; Watson, Jaime et al. (2014) Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo. Proc Natl Acad Sci U S A 111:16401-6
Parker, M Rockwell; Feng, Dianna; Chamuris, Brianna et al. (2014) Expression and nuclear translocation of glucocorticoid receptors in type 2 taste receptor cells. Neurosci Lett 571:72-7
Lee, Robert J; Chen, Bei; Redding, Kevin M et al. (2014) Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components. Innate Immun 20:606-17

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