Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
2R01DE009655-06
Application #
2130669
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1991-01-01
Project End
2000-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Aoh, Quyen L; Castle, Anna M; Hubbard, Charles H et al. (2009) SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling. Mol Biol Cell 20:1816-32
Liao, Haini; Zhang, Jie; Shestopal, Svetlana et al. (2008) Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis. Am J Physiol Cell Physiol 294:C797-809
Liao, Haini; Ellena, Jeff; Liu, Lixia et al. (2007) Secretory carrier membrane protein SCAMP2 and phosphatidylinositol 4,5-bisphosphate interactions in the regulation of dense core vesicle exocytosis. Biochemistry 46:10909-20
Liu, Lixia; Liao, Haini; Castle, Anna et al. (2005) SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells. Mol Biol Cell 16:4463-72
Castle, Anna; Castle, David (2005) Ubiquitously expressed secretory carrier membrane proteins (SCAMPs) 1-4 mark different pathways and exhibit limited constitutive trafficking to and from the cell surface. J Cell Sci 118:3769-80
Ellena, Jeffrey F; Moulthrop, Jason; Wu, Jing et al. (2004) Membrane position of a basic aromatic peptide that sequesters phosphatidylinositol 4,5 bisphosphate determined by site-directed spin labeling and high-resolution NMR. Biophys J 87:3221-33
Liu, Lixia; Guo, Zhenheng; Tieu, Quyen et al. (2002) Role of secretory carrier membrane protein SCAMP2 in granule exocytosis. Mol Biol Cell 13:4266-78
Guo, Zhenheng; Liu, Lixia; Cafiso, David et al. (2002) Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide. J Biol Chem 277:35357-63
Castle, J David; Guo, Zhenheng; Liu, Lixia (2002) Function of the t-SNARE SNAP-23 and secretory carrier membrane proteins (SCAMPs) in exocytosis in mast cells. Mol Immunol 38:1337-40
Hubbard, C; Singleton, D; Rauch, M et al. (2000) The secretory carrier membrane protein family: structure and membrane topology. Mol Biol Cell 11:2933-47

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