Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK002001-38
Application #
2133638
Study Section
Metabolism Study Section (MET)
Project Start
1978-05-01
Project End
1997-12-31
Budget Start
1996-02-27
Budget End
1996-12-31
Support Year
38
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Medical University of South Carolina
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425

  Publications

Robinson, Katherine A; Hegyi, Krisztina; Hannun, Yusuf A et al. (2014) Go-6976 reverses hyperglycemia-induced insulin resistance independently of cPKC inhibition in adipocytes. PLoS One 9:e108963
Robinson, Katherine A; Brock, Jonathan W; Buse, Maria G (2013) Posttranslational regulation of thioredoxin-interacting protein. J Mol Endocrinol 50:59-71
Klein, Amanda L; Berkaw, Mary N; Buse, Maria G et al. (2009) O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs. Mol Cell Proteomics 8:2733-45
Robinson, Katherine A; Buse, Maria G (2008) Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation. Am J Physiol Endocrinol Metab 294:E870-81
Robinson, Katherine A; Ball, Lauren E; Buse, Maria G (2007) Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab 292:E884-90
Ball, Lauren E; Berkaw, Mary N; Buse, Maria G (2006) Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1. Mol Cell Proteomics 5:313-23
Buse, Maria G (2006) Hexosamines, insulin resistance, and the complications of diabetes: current status. Am J Physiol Endocrinol Metab 290:E1-E8
Greene, E L; Nelson, B A; Robinson, K A et al. (2001) alpha-Lipoic acid prevents the development of glucose-induced insulin resistance in 3T3-L1 adipocytes and accelerates the decline in immunoreactive insulin during cell incubation. Metabolism 50:1063-9
Gazdag, A C; Wetter, T J; Davidson, R T et al. (2000) Lower calorie intake enhances muscle insulin action and reduces hexosamine levels. Am J Physiol Regul Integr Comp Physiol 278:R504-12
Koh, G; Robinson, K A; Buse, M G (1994) Delayed processing of the insulin proreceptor by hepatocytes from diabetic rats. Biochem Biophys Res Commun 204:725-31

Showing the most recent 10 out of 29 publications