Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK015851-23S1
Application #
2136954
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1978-08-01
Project End
1996-06-30
Budget Start
1994-07-01
Budget End
1996-06-30
Support Year
23
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Qadri, Ishtiaq; Hu, Ling-Jia; Iwahashi, Mieko et al. (2009) Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2). Toxicol Appl Pharmacol 234:281-92
Qadri, Ishtiaq; Iwahashi, Mieko; Kullak-Ublick, Gerd A et al. (2006) Hepatocyte nuclear factor (HNF) 1 and HNF4 mediate hepatic multidrug resistance protein 2 up-regulation during hepatitis C virus gene expression. Mol Pharmacol 70:627-36
Simon, Francis R; Iwahashi, Mieko; Hu, Ling-Jia et al. (2006) Hormonal regulation of hepatic multidrug resistance-associated protein 2 (Abcc2) primarily involves the pattern of growth hormone secretion. Am J Physiol Gastrointest Liver Physiol 290:G595-608
Qadri, Ishtiaq; Iwahashi, Mieko; Capasso, Juan M et al. (2004) Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1. Biochem J 378:919-28
Simon, Francis R; Fortune, John; Iwahashi, Mieko et al. (2004) Multihormonal regulation of hepatic sinusoidal Ntcp gene expression. Am J Physiol Gastrointest Liver Physiol 287:G782-94
Reichard, John F; Doorn, Jonathan A; Simon, Franz et al. (2003) Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal. Arch Biochem Biophys 411:243-50
Qadri, Ishtiaq; Iwahashi, Mieko; Simon, Francis (2002) Hepatitis C virus NS5A protein binds TBP and p53, inhibiting their DNA binding and p53 interactions with TBP and ERCC3. Biochim Biophys Acta 1592:193-204
Simon, Francis R; Fortune, John; Iwahashi, Mieko et al. (2002) Sexual dimorphic expression of ADH in rat liver: importance of the hypothalamic-pituitary-liver axis. Am J Physiol Gastrointest Liver Physiol 283:G646-55
Fiedler, J; Simon, F R; Iwahashi, M et al. (2001) Effect of peroxisome proliferator-activated receptor alpha activation on leukotriene B4 metabolism in isolated rat hepatocytes. J Pharmacol Exp Ther 299:691-7
Shiao, T; Iwahashi, M; Fortune, J et al. (2000) Structural and functional characterization of liver cell-specific activity of the human sodium/taurocholate cotransporter. Genomics 69:203-13

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