Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK021739-15
Application #
2137617
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1978-12-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Biochemistry
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Yoon, Dennis J; Chen, Kevin Y; Lopes, André M et al. (2017) Mathematical modeling of mutant transferrin-CRM107 molecular conjugates for cancer therapy. J Theor Biol 416:88-98
Das, Anupam; Nag, Sagarika; Mason, Anne B et al. (2016) Endosome-mitochondria interactions are modulated by iron release from transferrin. J Cell Biol 214:831-45
Mathies, Guinevere; Gast, Peter; Chasteen, N Dennis et al. (2015) Exploring the Fe(III) binding sites of human serum transferrin with EPR at 275 GHz. J Biol Inorg Chem 20:487-96
Luck, Ashley N; Mason, Anne B (2013) Structure and dynamics of drug carriers and their interaction with cellular receptors: focus on serum transferrin. Adv Drug Deliv Rev 65:1012-9
Deblonde, Gauthier J-P; Sturzbecher-Hoehne, Manuel; Mason, Anne B et al. (2013) Receptor recognition of transferrin bound to lanthanides and actinides: a discriminating step in cellular acquisition of f-block metals. Metallomics 5:619-26
Sturzbecher-Hoehne, Manuel; Goujon, Christophe; Deblonde, Gauthier J-P et al. (2013) Sensitizing curium luminescence through an antenna protein to investigate biological actinide transport mechanisms. J Am Chem Soc 135:2676-83
Luck, Ashley N; Bobst, Cedric E; Kaltashov, Igor A et al. (2013) Human serum transferrin: is there a link among autism, high oxalate levels, and iron deficiency anemia? Biochemistry 52:8333-41
Steere, Ashley N; Chasteen, N Dennis; Miller, Brendan F et al. (2012) Structure-based mutagenesis reveals critical residues in the transferrin receptor participating in the mechanism of pH-induced release of iron from human serum transferrin. Biochemistry 51:2113-21
Steere, Ashley N; Byrne, Shaina L; Chasteen, N Dennis et al. (2012) Kinetics of iron release from transferrin bound to the transferrin receptor at endosomal pH. Biochim Biophys Acta 1820:326-33
Luck, Ashley N; Mason, Anne B (2012) Transferrin-mediated cellular iron delivery. Curr Top Membr 69:3-35

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