Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK025705-11
Application #
3227555
Study Section
Metabolism Study Section (MET)
Project Start
1979-07-01
Project End
1989-09-30
Budget Start
1989-07-01
Budget End
1989-09-30
Support Year
11
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Type
Overall Medical
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Laychock, Suzanne G; Tian, Yingrao; Sessanna, Shawn M (2003) Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells. Diabetes 52:1986-93
Tian, Yingrao; Laychock, Suzanne G (2003) Prolactin regulates adenylyl cyclase and insulin secretion in rat pancreatic islets. Mol Cell Endocrinol 204:75-84
Srinivasan, Malathi; Laychock, Suzanne G; Hill, David J et al. (2003) Neonatal nutrition: metabolic programming of pancreatic islets and obesity. Exp Biol Med (Maywood) 228:15-23
Lee, B; Srinivasan, M; Aalinkeel, R et al. (2001) Mitochondrial-encoded gene regulation in rat pancreatic islets. Metabolism 50:200-6
Lee, B; Gai, W; Laychock, S G (2001) Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets. Endocrinology 142:1744-51
Tian, Y; Laychock, S G (2001) Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets. Diabetes 50:2505-13
Srinivasan, M; Aalinkeel, R; Song, F et al. (2000) Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula. Am J Physiol Endocrinol Metab 279:E1347-57
Laychock, S G; Duzen, J; Simpkins, C O (2000) Metallothionein induction in islets of Langerhans and insulinoma cells. Mol Cell Endocrinol 165:179-87
Lee, B; Laychock, S G (2000) Regulation of inositol trisphosphate receptor isoform expression in glucose-desensitized rat pancreatic islets: role of cyclic adenosine 3',5'-monophosphate and calcium. Endocrinology 141:1394-402
Lee, B; Jonas, J C; Weir, G C et al. (1999) Glucose regulates expression of inositol 1,4,5-trisphosphate receptor isoforms in isolated rat pancreatic islets. Endocrinology 140:2173-82

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