Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK027384-15
Application #
2137984
Study Section
Endocrinology Study Section (END)
Project Start
1980-07-01
Project End
1999-04-30
Budget Start
1996-05-07
Budget End
1997-04-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Inaba, Hidefumi; Moise, Leonard; Martin, William et al. (2013) Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides. Endocrinology 154:2234-43
Inaba, Hidefumi; Martin, William; Ardito, Matt et al. (2010) The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease. J Clin Endocrinol Metab 95:2909-16
De Groot, L J; Shin, Y Ha; Pan, D et al. (2009) Evaluation of T cell stimulation by thyrotropin-receptor epitopes in Graves' disease. J Endocrinol Invest 32:52-6
Inaba, Hidefumi; Martin, William; De Groot, Anne S et al. (2006) Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease. J Clin Endocrinol Metab 91:2286-94
Takara, Masaki; Kouki, Tsuyoshi; DeGroot, Leslie J (2003) CTLA-4 AT-repeat polymorphism reduces the inhibitory function of CTLA-4 in Graves' disease. Thyroid 13:1083-9
Gardine, C A; Gentile, F; Pellegrini, C et al. (2003) Multiple fragments of human TG are capable of inducing oral tolerance to whole human TG. J Endocrinol Invest 26:294-300
Kouki, T; Gardine, C A; Yanagawa, T et al. (2002) Relation of three polymorphisms of the CTLA-4 gene in patients with Graves' disease. J Endocrinol Invest 25:208-13
Gardine, C A; Kouki, T; DeGroot, L (2001) Characterization of the T lymphocyte subsets and lymphoid populations involved in the induction of low-dose oral tolerance to human thyroglobulin. Cell Immunol 212:1-15
Kouki, T; Sawai, Y; Gardine, C A et al. (2000) CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. J Immunol 165:6606-11
White, D M; Takeda, T; DeGroot, L J et al. (1997) Beta-trace gene expression is regulated by a core promoter and a distal thyroid hormone response element. J Biol Chem 272:14387-93

Showing the most recent 10 out of 56 publications