Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK028350-17
Application #
2138145
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1992-07-18
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Biochemistry
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Gainer, James V; Bellamine, Aouatef; Dawson, Elliott P et al. (2005) Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. Circulation 111:63-9
Kagawa, Norio; Senbonmatsu, Taka-aki; Satoh, Kumi et al. (2005) Tetracycline protects myocardium against ischemic injury. Front Biosci 10:608-19
Sewer, Marion B; Waterman, Michael R (2003) CAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells. J Biol Chem 278:8106-11
Kagawa, Norio; Cao, Qianwen; Kusano, Kazutomi (2003) Expression of human aromatase (CYP19) in Escherichia coli by N-terminal replacement and induction of cold stress response. Steroids 68:205-9
Nakagawa, Kiyoshi; Marji, Jackleen S; Schwartzman, Michal L et al. (2003) Androgen-mediated induction of the kidney arachidonate hydroxylases is associated with the development of hypertension. Am J Physiol Regul Integr Comp Physiol 284:R1055-62
Bellamine, Aouatef; Wang, Yarong; Waterman, Michael R et al. (2003) Characterization of the CYP4A11 gene, a second CYP4A gene in humans. Arch Biochem Biophys 409:221-7
Sewer, Marion B; Waterman, Michael R (2003) ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex. Microsc Res Tech 61:300-7
Sewer, M B; Waterman, M R (2002) cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A. J Mol Endocrinol 29:163-74
Sewer, Marion B; Nguyen, Viet Q; Huang, Ching-Jung et al. (2002) Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription. Endocrinology 143:1280-90
Sewer, M B; Waterman, M R (2002) Transcriptional complexes at the CYP17 CRS. Endocr Res 28:551-8

Showing the most recent 10 out of 78 publications