Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK028389-12
Application #
2138157
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1983-01-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical College of Georgia (MCG)
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Augusta
State
GA
Country
United States
Zip Code
30912
Brandsch, Matthias; Knutter, Ilka; Leibach, Frederick H (2004) The intestinal H+/peptide symporter PEPT1: structure-affinity relationships. Eur J Pharm Sci 21:53-60
Fujita, Takuya; Kishida, Takeshi; Wada, Miyuki et al. (2004) Functional characterization of brain peptide transporter in rat cerebral cortex: identification of the high-affinity type H+/peptide transporter PEPT2. Brain Res 997:52-61
Fei, Y J; Romero, M F; Krause, M et al. (2000) A novel H(+)-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H(+) channel and an exclusive expression in neurons. J Biol Chem 275:9563-71
Sugawara, M; Huang, W; Fei, Y J et al. (2000) Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J Pharm Sci 89:781-9
Fei, Y J; Sugawara, M; Liu, J C et al. (2000) cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1. Biochim Biophys Acta 1492:145-54
Fei, Y J; Fujita, T; Lapp, D F et al. (1998) Two oligopeptide transporters from Caenorhabditis elegans: molecular cloning and functional expression. Biochem J 332 ( Pt 2):565-72
Wang, H; Fei, Y J; Ganapathy, V et al. (1998) Electrophysiological characteristics of the proton-coupled peptide transporter PEPT2 cloned from rat brain. Am J Physiol 275:C967-75
Fei, Y J; Liu, J C; Fujita, T et al. (1998) Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras. Biochem Biophys Res Commun 246:39-44
Fei, Y J; Ganapathy, V; Leibach, F H (1998) Molecular and structural features of the proton-coupled oligopeptide transporter superfamily. Prog Nucleic Acid Res Mol Biol 58:239-61
Borner, V; Fei, Y J; Hartrodt, B et al. (1998) Transport of amino acid aryl amides by the intestinal H+/peptide cotransport system, PEPT1. Eur J Biochem 255:698-702

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