Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK030425-12S1
Application #
3229450
Study Section
Metabolism Study Section (MET)
Project Start
1982-01-01
Project End
1994-09-29
Budget Start
1994-07-01
Budget End
1994-09-29
Support Year
12
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Liu, Libin; Pilch, Paul F (2016) PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges. Elife 5:
Lo, Harriet P; Nixon, Susan J; Hall, Thomas E et al. (2015) The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. J Cell Biol 210:833-49
Breen, Michael R; Camps, Marta; Carvalho-Simoes, Francisco et al. (2012) Cholesterol depletion in adipocytes causes caveolae collapse concomitant with proteosomal degradation of cavin-2 in a switch-like fashion. PLoS One 7:e34516
Pilch, Paul F; Liu, Libin (2011) Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes. Trends Endocrinol Metab 22:318-24
Kandror, Konstantin V; Pilch, Paul F (2011) The sugar is sIRVed: sorting Glut4 and its fellow travelers. Traffic 12:665-71
Chao, Lily C; Wroblewski, Kevin; Zhang, Zidong et al. (2009) Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. Diabetes 58:2788-96
Bastiani, Michele; Liu, Libin; Hill, Michelle M et al. (2009) MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J Cell Biol 185:1259-73
Liu, Libin; Brown, Dennis; McKee, Mary et al. (2008) Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab 8:310-7
Pilch, P F (2008) The mass action hypothesis: formation of Glut4 storage vesicles, a tissue-specific, regulated exocytic compartment. Acta Physiol (Oxf) 192:89-101
Liu, Libin; Pilch, Paul F (2008) A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization. J Biol Chem 283:4314-22

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