Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK030603-15
Application #
2138415
Study Section
Physiology Study Section (PHY)
Project Start
1981-07-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Fisher, Kimberly D; Codina, Juan; Petrovic, Snezana et al. (2012) Pyk2 regulates H+-ATPase-mediated proton secretion in the outer medullary collecting duct via an ERK1/2 signaling pathway. Am J Physiol Renal Physiol 303:F1353-62
Codina, Juan; Opyd, Timothy S; Powell, Zachary B et al. (2011) pH-dependent regulation of the ýý-subunit of H+-K+-ATPase (HKýý2). Am J Physiol Renal Physiol 301:F536-43
Codina, Juan; DuBose Jr, Thomas D (2006) Molecular regulation and physiology of the H+,K+ -ATPases in kidney. Semin Nephrol 26:345-51
Codina, Juan; Liu, Jingfang; Bleyer, Anthony J et al. (2006) Phosphorylation of S955 at the protein kinase A consensus promotes maturation of the alpha subunit of the colonic H+,K+ -ATPase. J Am Soc Nephrol 17:1833-40
Codina, Juan; Li, Jian; Dubose Jr, Thomas D (2005) CD63 interacts with the carboxy terminus of the colonic H+-K+-ATPase to decrease [corrected] plasma membrane localization and 86Rb+ uptake. Am J Physiol Cell Physiol 288:C1279-86
Li, Jian; Codina, Juan; Petroske, Elizabeth et al. (2004) The effect of beta-subunit assembly on function and localization of the colonic H+,K+-ATPase alpha-subunit. Kidney Int 66:1068-75
Codina, Juan; Li, Jian; Dubose Jr, Thomas D (2004) A carboxy-terminus motif of HKalpha2 is necessary for assembly and function. Kidney Int 66:2283-92
Li, Jian; Codina, Juan; Petroske, Elizabeth et al. (2004) The carboxy terminus of the colonic H(+), K(+)-ATPase alpha-subunit is required for stable beta subunit assembly and function. Kidney Int 65:1301-10
Codina, Juan; Li, Jian; Hong, Yan et al. (2002) The gamma-Na+,K+-ATPase subunit assembles selectively with alpha1/beta1-Na+,K+-ATPase but not with the colonic H+,K+-ATPase. Kidney Int 61:967-74
DuBose Jr, T D (2000) Molecular and pathophysiologic mechanisms of hyperkalemic metabolic acidosis. Trans Am Clin Climatol Assoc 111:122-33; discussion 133-4

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