Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK031206-03
Application #
3229947
Study Section
Biochemistry Study Section (BIO)
Project Start
1983-08-01
Project End
1987-03-31
Budget Start
1985-08-01
Budget End
1987-03-31
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Overall Medical
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Muralimanoharan, Sribalasubashini; Kwak, Youn-Tae; Mendelson, Carole R (2018) Redox-Sensitive Transcription Factor NRF2 Enhances Trophoblast Differentiation via Induction of miR-1246 and Aromatase. Endocrinology 159:2022-2033
Zhang, Ming; Muralimanoharan, Sribalasubashini; Wortman, Alison C et al. (2016) Primate-specific miR-515 family members inhibit key genes in human trophoblast differentiation and are upregulated in preeclampsia. Proc Natl Acad Sci U S A 113:E7069-E7076
Luo, Yanmin; Kumar, Premlata; Chen, Chien-Cheng et al. (2014) Estrogen-related receptor ? serves a role in blood pressure homeostasis during pregnancy. Mol Endocrinol 28:965-75
Mendelson, Carole R (2013) GRTH: a key to understanding androgen-mediated germ cell signaling. Endocrinology 154:1967-9
Luo, Yanmin; Kumar, Premlata; Mendelson, Carole R (2013) Estrogen-related receptor ? (ERR?) regulates oxygen-dependent expression of voltage-gated potassium (K+) channels and tissue kallikrein during human trophoblast differentiation. Mol Endocrinol 27:940-52
Kumar, Premlata; Luo, Yanmin; Tudela, Carmen et al. (2013) The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation. Mol Cell Biol 33:1782-96
Chen, Chien-Cheng; Hardy, Daniel B; Mendelson, Carole R (2011) Progesterone receptor inhibits proliferation of human breast cancer cells via induction of MAPK phosphatase 1 (MKP-1/DUSP1). J Biol Chem 286:43091-102
Kumar, Premlata; Mendelson, Carole R (2011) Estrogen-related receptor gamma (ERRgamma) mediates oxygen-dependent induction of aromatase (CYP19) gene expression during human trophoblast differentiation. Mol Endocrinol 25:1513-26
Kumar, Premlata; Kamat, Amrita; Mendelson, Carole R (2009) Estrogen receptor alpha (ERalpha) mediates stimulatory effects of estrogen on aromatase (CYP19) gene expression in human placenta. Mol Endocrinol 23:784-93
Bukulmez, Orhan; Hardy, Daniel B; Carr, Bruce R et al. (2008) Androstenedione up-regulation of endometrial aromatase expression via local conversion to estrogen: potential relevance to the pathogenesis of endometriosis. J Clin Endocrinol Metab 93:3471-7

Showing the most recent 10 out of 29 publications