Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK033655-11
Application #
2139124
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1984-12-01
Project End
1997-06-30
Budget Start
1996-04-01
Budget End
1997-06-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Brelje, T Clark; Bhagroo, Nicholas V; Stout, Laurence E et al. (2008) Beneficial effects of lipids and prolactin on insulin secretion and beta-cell proliferation: a role for lipids in the adaptation of islets to pregnancy. J Endocrinol 197:265-76
Weinhaus, Anthony J; Stout, Laurence E; Bhagroo, Nicholas V et al. (2007) Regulation of glucokinase in pancreatic islets by prolactin: a mechanism for increasing glucose-stimulated insulin secretion during pregnancy. J Endocrinol 193:367-81
Sorenson, Robert L; Stout, Laurence E; Brelje, T Clark et al. (2007) Immunohistochemical evidence for the presence of glucokinase in the gonadotropes and thyrotropes of the anterior pituitary gland of rat and monkey. J Histochem Cytochem 55:555-66
Brelje, T Clark; Stout, Laurence E; Bhagroo, Nicholas V et al. (2004) Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of langerhans. Endocrinology 145:4162-75
Brelje, T Clark; Wessendorf, Martin W; Sorenson, Robert L (2002) Multicolor laser scanning confocal immunofluorescence microscopy: practical application and limitations. Methods Cell Biol 70:165-244
Brelje, T Clark; Svensson, Annika M; Stout, Laurence E et al. (2002) An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of Langerhans. J Histochem Cytochem 50:365-83
Weinhaus, A J; Bhagroo, N V; Brelje, T C et al. (2000) Dexamethasone counteracts the effect of prolactin on islet function: implications for islet regulation in late pregnancy. Endocrinology 141:1384-93
Porter, S E; Sorenson, R L; Dann, P et al. (1998) Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse. Endocrinology 139:3743-51
Weinhaus, A J; Bhagroo, N V; Brelje, T C et al. (1998) Role of cAMP in upregulation of insulin secretion during the adaptation of islets of Langerhans to pregnancy. Diabetes 47:1426-35
Stout, L E; Svensson, A M; Sorenson, R L (1997) Prolactin regulation of islet-derived INS-1 cells: characteristics and immunocytochemical analysis of STAT5 translocation. Endocrinology 138:1592-603

Showing the most recent 10 out of 32 publications