Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK034397-12
Application #
2139301
Study Section
Metabolism Study Section (MET)
Project Start
1984-09-01
Project End
1998-03-31
Budget Start
1996-05-01
Budget End
1998-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Elder, Deborah A; Prigeon, Ronald L; Wadwa, R Paul et al. (2006) Beta-cell function, insulin sensitivity, and glucose tolerance in obese diabetic and nondiabetic adolescents and young adults. J Clin Endocrinol Metab 91:185-91
Quddusi, Shaista; Vahl, Torsten P; Hanson, Kevin et al. (2003) Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans. Diabetes Care 26:791-8
Prigeon, Ronald L; Quddusi, Shaista; Paty, Breay et al. (2003) Suppression of glucose production by GLP-1 independent of islet hormones: a novel extrapancreatic effect. Am J Physiol Endocrinol Metab 285:E701-7
Ensinck, John W; Laschansky, Ellen C; Vogel, Robin E et al. (2003) Effect of ingested nutrients on the release of thrittene into the human circulation. J Clin Endocrinol Metab 88:4798-804
Ensinck, John W; Baskin, Denis G; Vahl, Torsten P et al. (2002) Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation. Endocrinology 143:2599-609
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D'Alessio, D A; Prigeon, R L; Ensinck, J W (1995) Enteral enhancement of glucose disposition by both insulin-dependent and insulin-independent processes. A physiological role of glucagon-like peptide I. Diabetes 44:1433-7
Burckhardt, B; Delco, F; Ensinck, J W et al. (1994) Cholecystokinin is a physiological regulator of gastric acid secretion in man. Eur J Clin Invest 24:370-6
D'Alessio, D A; Kahn, S E; Leusner, C R et al. (1994) Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal. J Clin Invest 93:2263-6
Hildebrand, P; Ensinck, J W; Ketterer, S et al. (1991) Effect of a cholecystokinin antagonist on meal-stimulated insulin and pancreatic polypeptide release in humans. J Clin Endocrinol Metab 72:1123-9

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