Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK035153-06
Application #
3233418
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1984-07-01
Project End
1991-03-31
Budget Start
1990-04-01
Budget End
1991-03-31
Support Year
6
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
Marquette University
Department
Type
Schools of Arts and Sciences
DUNS #
046929621
City
Milwaukee
State
WI
Country
United States
Zip Code
53201

  Publications

Mak, Piotr J; Denisov, Ilia G; Grinkova, Yelena V et al. (2011) Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. J Am Chem Soc 133:1357-66
Mak, Piotr J; Zhang, Haoming; Hollenberg, Paul F et al. (2010) Defining the structural consequences of mechanism-based inactivation of mammalian cytochrome P450 2B4 using resonance Raman spectroscopy. J Am Chem Soc 132:1494-5
Balakrishnan, Gurusamy; Ibrahim, Mohammed; Mak, Piotr J et al. (2009) Linking conformation change to hemoglobin activation via chain-selective time-resolved resonance Raman spectroscopy of protoheme/mesoheme hybrids. J Biol Inorg Chem 14:741-50
Balakrishnan, Gurusamy; Zhao, Xiaojie; Podstawska, Edyta et al. (2009) Subunit-selective interrogation of CO recombination in carbonmonoxy hemoglobin by isotope-edited time-resolved resonance Raman spectroscopy. Biochemistry 48:3120-6
Rwere, Freeborn; Mak, Piotr J; Kincaid, James R (2008) Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives. Biochemistry 47:12869-77
Denisov, Ilia G; Mak, Piotr J; Makris, Thomas M et al. (2008) Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450. J Phys Chem A 112:13172-9
Mak, Piotr J; Kincaid, James R (2008) Resonance Raman spectroscopic studies of hydroperoxo derivatives of cobalt-substituted myoglobin. J Inorg Biochem 102:1952-7
Mak, Piotr J; Kaluka, Daniel; Manyumwa, Munyaradzi Edith et al. (2008) Defining resonance Raman spectral responses to substrate binding by cytochrome P450 from Pseudomonas putida. Biopolymers 89:1045-53
Mak, Piotr J; Im, Sang-Choul; Zhang, Haoming et al. (2008) Resonance Raman studies of cytochrome P450 2B4 in its interactions with substrates and redox partners. Biochemistry 47:3950-63
Mak, Piotr J; Denisov, Ilia G; Victoria, Doreen et al. (2007) Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle. J Am Chem Soc 129:6382-3

Showing the most recent 10 out of 27 publications