Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK036424-10
Application #
2139791
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1986-02-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Liu, H; Kublaoui, B; Pilch, P F et al. (2000) Insulin activation of mitogen-activated protein (MAP) kinase and Akt is phosphatidylinositol 3-kinase-dependent in rat adipocytes. Biochem Biophys Res Commun 274:845-51
Calera, M R; Vallega, G; Pilch, P F (2000) Dynamics of protein-tyrosine phosphatases in rat adipocytes. J Biol Chem 275:6308-12
Woldin, C N; Hing, F S; Lee, J et al. (1999) Structural studies of the detergent-solubilized and vesicle-reconstituted insulin receptor. J Biol Chem 274:34981-92
Hamm, J K; el Jack, A K; Pilch, P F et al. (1999) Role of PPAR gamma in regulating adipocyte differentiation and insulin-responsive glucose uptake. Ann N Y Acad Sci 892:134-45
Lin, B; Coughlin, S; Pilch, P F (1998) Bidirectional regulation of uncoupling protein-3 and GLUT-4 mRNA in skeletal muscle by cold. Am J Physiol 275:E386-91
Calera, M R; Pilch, P F (1998) Induction of Akt-2 correlates with differentiation in Sol8 muscle cells. Biochem Biophys Res Commun 251:835-41
Zhou, M; Sevilla, L; Vallega, G et al. (1998) Insulin-dependent protein trafficking in skeletal muscle cells. Am J Physiol 275:E187-96
Calera, M R; Martinez, C; Liu, H et al. (1998) Insulin increases the association of Akt-2 with Glut4-containing vesicles. J Biol Chem 273:7201-4
Kummer, J L; Calera, M R; Pilch, P F (1998) Separation of IRS-1 and PI3-kinase from GLUT4 vesicles in rat skeletal muscle. Biochem Biophys Res Commun 246:282-6
Kandror, K V; Pilch, P F (1998) Multiple endosomal recycling pathways in rat adipose cells. Biochem J 331 ( Pt 3):829-35

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