Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK037124-03
Application #
3235881
Study Section
Biochemistry Study Section (BIO)
Project Start
1987-02-01
Project End
1989-09-30
Budget Start
1989-02-01
Budget End
1989-09-30
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

McDonald, Charles J; Acheff, Eric; Kennedy, Ryan et al. (2015) Effect of lysine to alanine mutations on the phosphate activation and BPTES inhibition of glutaminase. Neurochem Int 88:10-4
Curthoys, Norman P; Gstraunthaler, Gerhard (2014) pH-responsive, gluconeogenic renal epithelial LLC-PK1-FBPase+cells: a versatile in vitro model to study renal proximal tubule metabolism and function. Am J Physiol Renal Physiol 307:F1-F11
Curthoys, Norman P; Moe, Orson W (2014) Proximal tubule function and response to acidosis. Clin J Am Soc Nephrol 9:1627-38
Freund, Dana M; Prenni, Jessica E; Curthoys, Norman P (2013) Proteomic profiling of the mitochondrial inner membrane of rat renal proximal convoluted tubules. Proteomics 13:2495-9
Freund, Dana M; Prenni, Jessica E (2013) Improved Detection of Quantitative Differences Using a Combination of Spectral Counting and MS/MS Total Ion Current. J Proteome Res :
Schauer, Kevin L; Freund, Dana M; Prenni, Jessica E et al. (2013) Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis. Am J Physiol Renal Physiol 305:F628-40
Freund, Dana M; Prenni, Jessica E; Curthoys, Norman P (2013) Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis. Am J Physiol Renal Physiol 304:F145-55
Walmsley, Scott J; Freund, Dana M; Curthoys, Norman P (2012) Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule. Am J Physiol Renal Physiol 302:F1465-77
Hartwick, Erik W; Curthoys, Norman P (2012) BPTES inhibition of hGA(124-551), a truncated form of human kidney-type glutaminase. J Enzyme Inhib Med Chem 27:861-7
Gummadi, Lakshmi; Taylor, Lynn; Curthoys, Norman P (2012) Concurrent binding and modifications of AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells. Am J Physiol Renal Physiol 303:F1545-54

Showing the most recent 10 out of 53 publications