Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK038201-09
Application #
2016225
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1986-04-01
Project End
1999-11-30
Budget Start
1996-09-01
Budget End
1996-11-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Charlotte
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Charlotte
State
NC
Country
United States
Zip Code
28223

  Publications

Norris, Eric J; Larion, Sebastian; Culberson, Catherine R et al. (2013) Hydrogen sulfide differentially affects the hepatic vasculature in response to phenylephrine and endothelin 1 during endotoxemia. Shock 39:168-75
Norris, Eric J; Culberson, Catherine R; Narasimhan, Sriram et al. (2011) The liver as a central regulator of hydrogen sulfide. Shock 36:242-50
Kwok, Willson; Clemens, Mark G (2010) Targeted mutation of Cav-1 alleviates the effect of endotoxin in the inhibition of ET-1-mediated eNOS activation in the liver. Shock 33:392-8
Kwok, Willson; Lee, Sang Ho; Culberson, Cathy et al. (2009) Caveolin-1 mediates endotoxin inhibition of endothelin-1-induced endothelial nitric oxide synthase activity in liver sinusoidal endothelial cells. Am J Physiol Gastrointest Liver Physiol 297:G930-9
Miller, Andrew M; Zhang, Jian X (2009) Altered endothelin-1 signaling in production of thromboxane A2 in kupffer cells from bile duct ligated rats. Cell Mol Immunol 6:441-52
Xu, Hongzhi; Lee, Charles Y; Clemens, Mark G et al. (2008) Inhibition of TXA synthesis with OKY-046 improves liver preservation by prolonged hypothermic machine perfusion in rats. J Gastroenterol Hepatol 23:e212-20
Lee, Sang Ho; Culberson, Cathy; Korneszczuk, Katarzyna et al. (2008) Differential mechanisms of hepatic vascular dysregulation with mild vs. moderate ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol 294:G1219-26
Karaa, Amel; Thompson, Kyle J; McKillop, Iain H et al. (2008) S-adenosyl-L-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model. Shock 30:197-205
Miller, Andrew M; Masrorpour, Mina; Klaus, Christian et al. (2007) LPS exacerbates endothelin-1 induced activation of cytosolic phospholipase A2 and thromboxane A2 production from Kupffer cells of the prefibrotic rat liver. J Hepatol 46:276-85
Keller, Steve; Karaa, Amel; Paxian, Markus et al. (2006) Inhibition of endothelin-1-mediated up-regulation of iNOS by bosentan ameliorates endotoxin-induced liver injury in cirrhosis. Shock 25:306-13

Showing the most recent 10 out of 62 publications