Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK040218-08S2
Application #
2141233
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1989-02-15
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Liu, F; Shao, L E; Yu, J (2000) Truncated activin type II receptor inhibits erythroid differentiation in K562 cells. J Cell Biochem 78:24-33
Dialynas, D P; Shao, L E; Hinojosa, A G et al. (1999) Functional and biochemical characterization of a novel human macrophage-derived negative regulator of haematopoiesis. Cytokine 11:985-95
Yu, E W; Dolter, K E; Shao, L E et al. (1998) Suppression of IL-6 biological activities by activin A and implications for inflammatory arthropathies. Clin Exp Immunol 112:126-32
Dolter, K E; Palyash, J C; Shao, L E et al. (1998) Analysis of activin A gene expression in human bone marrow stromal cells. J Cell Biochem 70:8-21
Shao, L E; Frigon Jr, N L; Yu, A et al. (1998) Contrasting effects of inflammatory cytokines and glucocorticoids on the production of activin A in human marrow stromal cells and their implications. Cytokine 10:227-35
Dialynas, D P; Lee, M J; Shao, L E et al. (1997) Phenotypic and functional characterization of a new human macrophage cell line K1m demonstrating immunophagocytic activity and signalling through HLA class II. Immunology 90:470-6
Dialynas, D P; Tan, P C; Yu, J (1997) Cytokine modulatable signalling through macrophage HLA class II. 1. IFN-gamma upregulates the efficiency of Ca2+ mobilization in response to ligation of macrophage HLA-DP. J Interferon Cytokine Res 17:671-9
Dialynas, D P; Tan, P C; Huhn, G D et al. (1997) Characterization of a new human macrophage cell line 2MAC. 1. Expression of functional macrophage CD16 (Fc gammaRIIIA/gamma) and tissue factor induction on ligation of HLA-DR. Cell Immunol 177:182-93
Yu, J; Dolter, K E (1997) Production of activin A and its roles in inflammation and hematopoiesis. Cytokines Cell Mol Ther 3:169-77
Diccianni, M B; Batova, A; Yu, J et al. (1997) Shortened survival after relapse in T-cell acute lymphoblastic leukemia patients with p16/p15 deletions. Leuk Res 21:549-58

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