Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK040339-08
Application #
2141299
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1988-09-20
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Howard, Paul W; Jue, Shall F; Maurer, Richard A (2009) Expression of the synaptotagmin I gene is enhanced by binding of the pituitary-specific transcription factor, POU1F1. Mol Endocrinol 23:1563-71
Kievit, Paul; Maurer, Richard A (2005) The pituitary-specific transcription factor, Pit-1, can direct changes in the chromatin structure of the prolactin promoter. Mol Endocrinol 19:138-47
Kievit, P; Lauten, J D; Maurer, R A (2001) Analysis of the role of the mitogen-activated protein kinase in mediating cyclic-adenosine 3',5'-monophosphate effects on prolactin promoter activity. Mol Endocrinol 15:614-24
Howard, P W; Maurer, R A (2001) A point mutation in the LIM domain of Lhx3 reduces activation of the glycoprotein hormone alpha-subunit promoter. J Biol Chem 276:19020-6
Howard, P W; Maurer, R A (2000) Identification of a conserved protein that interacts with specific LIM homeodomain transcription factors. J Biol Chem 275:13336-42
Wang, Y H; Jue, S F; Maurer, R A (2000) Thyrotropin-releasing hormone stimulates phosphorylation of the epidermal growth factor receptor in GH3 pituitary cells. Mol Endocrinol 14:1328-37
Wang, Y H; Maurer, R A (1999) A role for the mitogen-activated protein kinase in mediating the ability of thyrotropin-releasing hormone to stimulate the prolactin promoter. Mol Endocrinol 13:1094-104
Nowakowski, B E; Okimura, Y; Maurer, R A (1997) Characterization of DNA regions mediating the ability of Ca2+/calmodulin dependent protein kinase II to stimulate prolactin promoter activity. Mol Cell Endocrinol 132:109-16
Liang, J; Moye-Rowley, S; Maurer, R A (1995) In vivo mutational analysis of the DNA binding domain of the tissue-specific transcription factor, Pit-1. J Biol Chem 270:25520-5
Howard, P W; Maurer, R A (1995) A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways. J Biol Chem 270:20930-6

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