Dietary N-3 Fatty Acids and Expression of Cyclooxygenase

Hwang, Daniel H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK041868-06
• Application #: 2141951
• Study Section: Nutrition Study Section (NTN)
• Project Start: 1989-06-01
• Project End: 1998-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 6
• Fiscal Year: 1996

Institution

• Name: Lsu Pennington Biomedical Research Center
• Type: Organized Research Units
• City: Baton Rouge
• State: LA
• Country: United States
• Zip Code: 70808

Publications

Snodgrass, Ryan G; Huang, Shurong; Choi, Il-Whan et al. (2013) Inflammasome-mediated secretion of IL-1? in human monocytes through TLR2 activation; modulation by dietary fatty acids. J Immunol 191:4337-47

Huang, Shurong; Rutkowsky, Jennifer M; Snodgrass, Ryan G et al. (2012) Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. J Lipid Res 53:2002-13

Zhao, Ling; Lee, Joo Y; Hwang, Daniel H (2011) Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals. Nutr Rev 69:310-20

Adams, Sean H; Hoppel, Charles L; Lok, Kerry H et al. (2009) Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women. J Nutr 139:1073-81

Wong, Scott W; Kwon, Myung-Ja; Choi, Augustine M K et al. (2009) Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. J Biol Chem 284:27384-92

Zhao, Ling; Lee, Joo Y; Hwang, Daniel H (2008) The phosphatidylinositol 3-kinase/Akt pathway negatively regulates Nod2-mediated NF-kappaB pathway. Biochem Pharmacol 75:1515-25

Huang, Shurong; Zhao, Ling; Kim, Kihoon et al. (2008) Inhibition of Nod2 signaling and target gene expression by curcumin. Mol Pharmacol 74:274-81

Zhao, Ling; Kwon, Myung-Ja; Huang, Shurong et al. (2007) Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells. J Biol Chem 282:11618-28

Youn, Hyung S; Saitoh, Shin I; Miyake, Kensuke et al. (2006) Inhibition of homodimerization of Toll-like receptor 4 by curcumin. Biochem Pharmacol 72:62-9

Youn, Hyung S; Lee, Joo Y; Saitoh, Shin I et al. (2006) Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea. Biochem Pharmacol 72:850-9