Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK042033-07
Application #
2142059
Study Section
Nutrition Study Section (NTN)
Project Start
1990-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Nutrition
Type
Schools of Earth Sciences/Natur
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Schaevitz, Laura R; Picker, Jonathan D; Rana, Jasmine et al. (2012) Glutamate carboxypeptidase II and folate deficiencies result in reciprocal protection against cognitive and social deficits in mice: implications for neurodevelopmental disorders. Dev Neurobiol 72:891-905
MacFarlane, Amanda J; Perry, Cheryll A; Girnary, Hussein H et al. (2009) Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem 284:1533-9
Lawrance, Andrea K; Deng, Liyuan; Brody, Lawrence C et al. (2007) Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. J Nutr Biochem 18:305-12
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Lim, Unhee; Peng, Kun; Shane, Barry et al. (2005) Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr 135:1989-94
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Dayal, Sanjana; Devlin, Angela M; McCaw, Ryan B et al. (2005) Cerebral vascular dysfunction in methionine synthase-deficient mice. Circulation 112:737-44
O'Leary, Valerie B; Mills, James L; Pangilinan, Faith et al. (2005) Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association. Mol Genet Metab 85:220-7
Davis, Steven R; Stacpoole, Peter W; Williamson, Jerry et al. (2004) Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor. Am J Physiol Endocrinol Metab 286:E272-9
Prasannan, Priya; Pike, Schuyler; Peng, Kun et al. (2003) Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls. J Biol Chem 278:43178-87

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