Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043695-06
Application #
2143154
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1991-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Physiology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Mueckler, Mike; Thorens, Bernard (2013) The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med 34:121-38
Mueckler, Mike; Makepeace, Carol (2012) Ligand-induced movements of inner transmembrane helices of Glut1 revealed by chemical cross-linking of di-cysteine mutants. PLoS One 7:e31412
Alisio, Arturo; Mueckler, Mike (2010) Purification and characterization of mammalian glucose transporters expressed in Pichia pastoris. Protein Expr Purif 70:81-7
Mueckler, Mike; Makepeace, Carol (2009) Model of the exofacial substrate-binding site and helical folding of the human Glut1 glucose transporter based on scanning mutagenesis. Biochemistry 48:5934-42
Song, Xiao Mei; Hresko, Richard C; Mueckler, Mike (2008) Identification of amino acid residues within the C terminus of the Glut4 glucose transporter that are essential for insulin-stimulated redistribution to the plasma membrane. J Biol Chem 283:12571-85
Mueckler, Mike; Makepeace, Carol (2006) Transmembrane segment 12 of the Glut1 glucose transporter is an outer helix and is not directly involved in the transport mechanism. J Biol Chem 281:36993-8
Mueckler, Mike; Makepeace, Carol (2005) Cysteine-scanning mutagenesis and substituted cysteine accessibility analysis of transmembrane segment 4 of the Glut1 glucose transporter. J Biol Chem 280:39562-8
Mueckler, Mike; Makepeace, Carol (2004) Analysis of transmembrane segment 8 of the GLUT1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility. J Biol Chem 279:10494-9
Mueckler, Mike; Roach, William; Makepeace, Carol (2004) Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix. J Biol Chem 279:46876-81
Alisio, Arturo; Mueckler, Mike (2004) Relative proximity and orientation of helices 4 and 8 of the GLUT1 glucose transporter. J Biol Chem 279:26540-5

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