Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043816-06
Application #
2143322
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Nighot, Meghali P; Nighot, Prashant K; Ma, Thomas Y et al. (2015) Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion. PLoS One 10:e0138174
Cuppoletti, John; Malinowska, Danuta H; Tewari, Kirti P et al. (2004) SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents. Am J Physiol Cell Physiol 287:C1173-83
Cuppoletti, John; Tewari, Kirti P; Sherry, Ann M et al. (2004) Sites of protein kinase A activation of the human ClC-2 Cl(-) channel. J Biol Chem 279:21849-56
Malinowska, Danuta H; Sherry, Ann M; Tewari, Kirti P et al. (2004) Gastric parietal cell secretory membrane contains PKA- and acid-activated Kir2.1 K+ channels. Am J Physiol Cell Physiol 286:C495-506
Sherry, A M; Malinowska, D H; Morris, R E et al. (2001) Localization of ClC-2 Cl- channels in rabbit gastric mucosa. Am J Physiol Cell Physiol 280:C1599-606
Cuppoletti, J; Tewari, K P; Sherry, A M et al. (2001) ClC-2 Cl- channels in human lung epithelia: activation by arachidonic acid, amidation, and acid-activated omeprazole. Am J Physiol Cell Physiol 281:C46-54
Tewari, K P; Malinowska, D H; Sherry, A M et al. (2000) PKA and arachidonic acid activation of human recombinant ClC-2 chloride channels. Am J Physiol Cell Physiol 279:C40-50
Stroffekova, K; Kupert, E Y; Malinowska, D H et al. (1998) Identification of the pH sensor and activation by chemical modification of the ClC-2G Cl- channel. Am J Physiol 275:C1113-23
Sherry, A M; Stroffekova, K; Knapp, L M et al. (1997) Characterization of the human pH- and PKA-activated ClC-2G(2 alpha) Cl- channel. Am J Physiol 273:C384-93
Huang, P; Stroffekova, K; Cuppoletti, J et al. (1996) Functional expression of the cystic fibrosis transmembrane conductance regulator in yeast. Biochim Biophys Acta 1281:80-90

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