Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044319-11
Application #
6624869
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Hamilton, Frank A
Project Start
1992-09-30
Project End
2004-11-30
Budget Start
2002-12-01
Budget End
2003-11-30
Support Year
11
Fiscal Year
2003
Total Cost
$446,516
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
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Aden, Konrad; Tran, Florian; Ito, Go et al. (2018) ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. J Exp Med 215:2868-2886
Clancy-Thompson, Eleanor; Ali, Lestat; Bruck, Patrick T et al. (2018) IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells. Cancer Immunol Res 6:25-35
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Gensollen, Thomas; Blumberg, Richard S (2017) Correlation between early-life regulation of the immune system by microbiota and allergy development. J Allergy Clin Immunol 139:1084-1091
Schrumpf, Elisabeth; Kummen, Martin; Valestrand, Laura et al. (2017) The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation. J Hepatol 66:382-389
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Tschurtschenthaler, Markus; Adolph, Timon E; Ashcroft, Jonathan W et al. (2017) Defective ATG16L1-mediated removal of IRE1? drives Crohn's disease-like ileitis. J Exp Med 214:401-422
Kaser, Arthur; Blumberg, Richard S (2017) The road to Crohn's disease. Science 357:976-977
Zeissig, Sebastian; Peuker, Kenneth; Iyer, Shankar et al. (2017) CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation. Proc Natl Acad Sci U S A 114:10449-10454

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