Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK045365-06S1
Application #
2759633
Study Section
Hematology Subcommittee 2 (HEM)
Program Officer
Badman, David G
Project Start
1998-06-01
Project End
1998-07-31
Budget Start
1998-06-01
Budget End
1998-07-31
Support Year
6
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Vierstra, Jeff; Reik, Andreas; Chang, Kai-Hsin et al. (2015) Functional footprinting of regulatory DNA. Nat Methods 12:927-30
Hughey, Jeffery R; Du, Meijun; Li, Qiliang et al. (2012) A search for ? thalassemia mutations in 4000 year old ancient DNAs of Minoan Cretans. Blood Cells Mol Dis 48:7-10
Fang, Xiangdong; Yin, Wenxuan; Xiang, Ping et al. (2009) The higher structure of chromatin in the LCR of the beta-globin locus changes during development. J Mol Biol 394:197-208
Hu, Jie Hong; Navas, Patrick; Cao, Hua et al. (2007) Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation. J Mol Biol 366:1064-73
Fang, Xiangdong; Xiang, Ping; Yin, Wenxuan et al. (2007) Cooperativeness of the higher chromatin structure of the beta-globin locus revealed by the deletion mutations of DNase I hypersensitive site 3 of the LCR. J Mol Biol 365:31-7
Olave, Ivan A; Doneanu, Catalin; Fang, Xiangdong et al. (2007) Purification and identification of proteins that bind to the hereditary persistence of fetal hemoglobin -198 mutation in the gamma-globin gene promoter. J Biol Chem 282:853-62
Navas, Patrick A; Li, Qiliang; Peterson, Kenneth R et al. (2006) Investigations of a human embryonic globin gene silencing element using YAC transgenic mice. Exp Biol Med (Maywood) 231:328-34
Nishino, Tamon; Cao, Hua; Stamatoyannopoulos, George et al. (2006) Effects of human gamma-globin in murine beta-thalassaemia. Br J Haematol 134:100-8
Li, Qiliang; Fang, Xiangdong; Olave, Ivan et al. (2006) Transcriptional potential of the gamma-globin gene is dependent on the CACCC box in a developmental stage-specific manner. Nucleic Acids Res 34:3909-16
Yu, Man; Han, Hemei; Xiang, Ping et al. (2006) Autonomous silencing as well as competition controls gamma-globin gene expression during development. Mol Cell Biol 26:4775-81

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